Background: Pregnancy related deathsareconsidered one of the chiefcauses of premature women's death worldwide as about 500000 ladies diedyearlyfrom this cause, about 25.0% of these mortalities are due to hemorrhage. Aim of the work: Comparison of the safety and effectiveness of carbetocin over oxytocin in prevention of postpartum Hemorrhagedue to uterine atony after vaginal deliveries and cesarean sections. Patients and Methods: : This computerized random cross sectional prospective comparative study included a total 400 pregnant women who were going to deliver, attending at Obstetric and Gynecological

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