Background: The most common cause of hospital admission in the first month of life is the neonatal jaundice. Some factors [e.g., prenatal, neonatal factors, maternal factors, and environmental factors (such as zinc) influence the frequency of neonatal jaundice. In terms of neonates, it is proposed that there is a correlation between serum zinc quality and hyperbilirubinemia. Aim of the work: To evaluate the level of serum zinc in term neonates with indirect hyperbilirubinemia. Patients and methods: A case control study carried out at the neonatal intensive care unit (NICU) and pediatric outpatient clinic of New Damietta, Al-Azhar University Hospital, from June 2018 to February 2019. It included 75 neonates with neonatal jaundice as cases group and 75 healthy neonates of matched age and sex as a control group. All were assessed clinically and serum zinc levels were determined and documented. Results: Level of serum zinc in neonates with non-hemolytic hyperbilirubinemia (103.3±36.56 ug/dl) was significantly lower than healthy neonates without jaundice (128.62 ± 40.83 ug/dl) and zinc deficiency in jaundiced neonates (25.3%) was statistically significant more than healthy neonates)6.7%). There was no significant relation between the level of serum zinc and other factors like the maternal age, parity, pattern of feeding, gender and weight, but there was significant correlation with maternal zinc intake during pregnancy. Conclusion: We concluded that serum zinc level in term neonates with neonatal jaundice was statistically significant decreased than healthy term neonates.
Background: Febrile seizures are non-epileptic types of seizure that occur frequently during early childhood. Multiple factors are implicated in the pathogenesis of these types of seizures. Iron deficiency might play as an etiological or, at least, augmenting factor in the development of febrile seizures.Objective: To study iron status among children with simple febrile seizures, and to estimate the prevalence of iron deficiency between them. Patients and methods: A case-control study included 100 febrile children aged 6 months to 60 months, and were ascribed to 2 groups; 50 children with simple febrile seizures [case group], and 50 children who had febrile disease without occurrence of seizures [control group]. Venous samples were obtained for the analysis of complete blood count, and iron indices [serum ferritin, serum iron and total iron binding capacity]. Results: The peak temperature was significantly elevated among the case group [P=0.03]. Regarding iron profile, compared to controls, the case group had significantly lower iron [54.24±16.04 vs. 62.6±16.02; P=0.011], and lower ferritin [37.612±19.85 vs. 80.624±31.57; P <0.001]. Correlation analysis revealed a significant negative correlation between serum ferritin and frequency of febrile seizures [P=0.025]Conclusions: Iron deficiency and iron deficiency anemia were more common among children with simple febrile seizures, and they were associated with increase in the duration and frequency of seizures. Special attention should be paid for the assessment of iron status among children with febrile seizures.
Background: Respiratory distress syndrome [RDS] is among the most common diseases in preterm infants. Numerous causes of RDS have been recently diagnosed and researchers have identified the presence of low serum carnitine in preterm infants with RDS.The aim of this study: to evaluate serum carnitine levels in preterm infants with RDS.Patients and methods: Eighty preterm infants were divided into two groups; group 1 consisted of 50 preterm with RDS in the first 6h of life constituted Group [A] as they were preterm infants with RDS with normal serum carnitine levels while Group [B] represented infants with carnitine deficiency. Control group 2 consisted of 30 preterm infants without RDS in the first 6 h of life. All cases and their mothers included in the study were subjected to a thorough history taking, thorough clinical examination and measurement of serum carnitine. Results:The cases groups had significantly lower serum L-carnitine than the controls group [25.56 ± 11.14 vs. 34.53 ± 2.54], and carnitine deficiency in RDS cases [32%]. Concerning weight, cases with carnitine deficiency had higher weight than cases with normal carnitine and control. With regard to clinical manifestations, there was a statistically significant difference between the cases subgroups in Down score indicting severe RDS in cases with carnitine deficiency. There was a statistically significant difference among cases subgroups regarding radiological findings. The cases with carnitine deficiency had worse X-ray, more need for surfactant therapy and MV than the cases with normal carnitine. Conclusion:Preterm neonates with RDS were demonstrated to be associated with a significant reduction in carnitine level compared to RDS-free preterm ones.
Background: Favism means a hemolytic response to the ingesting of fava beans, also identified as broad beans. Aim: Assess effect of health education program for mothers their children diagnosed with favism. Research design: A quasi-experimental design. Setting: Pediatric Outpatient Clinic in Al-Azhar University Hospital (New Damietta City), Damietta Governorate, Egypt. Sample: A convenient sample (72) of mothers their children diagnosed with favism. Tool: An interviewing questionnaire used divided to five parts: Part (1):Demographic characteristics for mothers' and their children. Part (2): Children medical history. Part (3): Mothers' knowledge regarding favism; Part (4): Mothers' attitude regarding favism; Part (5): Mothers' reported practice regarding favism. Results: present study cleared, highly statistically significant enhancement of mothers' knowledge, attitude and reported practice post health education program than pre (5.874±2.341, 4.16±2.26 and 2.324±2.410),( 25.742±2.845, 23.63±2.53and 6.945± 2.748)respectively .Conclusion: The health education program was effective in enhancement mothers' knowledge, attitude and practices regarding favism .Recommendations: Further researches and health education program are needed in other settings to outreach mothers for the promotion of favism knowledge, attitude and consequently practice to prevent favism complications for their children.
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