Background: Evaluating the effect of low level laser therapy (LLLT) on miniscrew displacement and gingival inflammation around miniscrew. Methods: Twenty-four buccal intra-alveolar miniscrews were inserted on right and left sides for maxillary canine retraction after 1st premolar extraction. The sides were randomly allocated into experimental side; which received low level laser (LLL) application after miniscrew insertion and a control side which received no Laser application. Miniscrews on both sides were loaded with 150gm of force, 14 days after their insertion. Gingival inflammation around miniscrew was assessed using gingival index throughout the study period and miniscrew displacement was evaluated using CBCT after six months of active canine retraction.Results: All miniscrews showed displacement with no significant difference between control and experimental sides. LLLT successfully reduced gingival inflammation at miniscrew site, as evidenced by gingival index.Conclusions: LLLT can be proposed as clinical procedures to add in success of miniscrews , however LLLT does not decrease miniscrew displacement .Trial registration: NCT05092633 ClinicalTrials.gov. Registered 25th of October 2021, https://clinicaltrials.gov/ct2/show/NCT05092633
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