Background: Khat is a natural stimulant from the Catha edulis plant containing several chemical components, which can explain palpitation as a frequent symptom that develops during or after khat chewing. Aims: To study the effects of khat chewing on cardiac rhythm. Methods: We selected sixty khat-chewing Yemeni individuals and divided them into two groups: 30 were cardiac patients and the other 30 were non-cardiac individuals. All 60 individuals underwent 24 hours holter monitoring for 2 consequent days; the first was a khat-free day and the next was a khat-chewing day. The two groups were matched for age, sex, smoking habit, BSA, systolic and diastolic blood pressure. Non sustained Ventricular Tachycardia (VT) was defined as 3 or more wide QRS complexes at a rate of 120 beats/min and for a period less than 20 seconds. Results: The non-sustained VT was found on 7 (23.3%) of the 30 cardiac patients on a khat-chewing day compared to 2 patients (6.6%) on a khat-free day (p < 0.01). A significant difference was also seen among the normal individuals; 1 patient (3.3%) developed short runs of VT on a khat-chewing day compared to non VT on a khat-free day. Conclusions: 1) Serious arrhythmias occur in both cardiac and noncardiac individuals during khat chewing days although they are more prominent among cardiac patients. 2) This may indicate beta-blocker usage for high risk khat chewers before khat chewing.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.