Cancer is a growing burden globally. Radiotherapy has proven to be a critical and cost-effective treatment modality for a cure in greater than 50% of cancer patients. There are numerous obstacles and challenges in establishing new radiotherapy facilities and programs, especially in low- and middle-income countries. It is known that the clinical aspect, as well as procedure related to the physical and technical aspect of patient treatment, needs to be subjected to careful planning in order to ensure safe and high-quality radiotherapy. This process required the engagement of various professionals from different backgrounds.This chapter aims to define radiotherapy value, assessing a radiation facility’s clinical, infrastructure, and resources need to establish a new radiotherapy facility.
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