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Our data suggest that ATX activity and gene expression are reliable diagnostic and prognostic tools in thyroid carcinoma compared to sICAM-1.

Aim: The aim of this study is to evaluate initial and short-term result of duplex guided angioplasty (DGA) for treatment of femoropopliteal arterial lesions. Methods: From October 2017 to September 2020, 50 limbs in 50 patients (30 males) underwent DGA in our institution. The study was conducted on patients suffered from chronic lower limb ischemia of grade IIb, III and IV (according to Fontaine Classifications) resulting from femoropopliteal lesions (occlusion or stenosis). Arterial access was done under duplex guidance followed by advancing a guidewire across the diseased femoropopliteal segment(s). The diseased segment(s) were then balloon-dilated. Intimal dissection or residual stenosis causing diameter reductions greater than 30% were stented with a self-expandable stent under duplex guidance. Completion duplex examinations and ankle brachial indices were obtained after the procedure. Results: The mean age of patients was 64 ±8 years. Critical ischemia was the indication in 44%, and disabling claudication was the indication in 6% of cases. Technical success was achieved in 46 cases (92%). 31 cases (62%) went through transluminal crossing of the lesions using duplex guidance alone, 11 cases (22%) went transluminally using duplex combined with contrast-free fluoroscopic assistance and 4 cases (8%) was subjected to subintimal angioplasty using combined techniques. Stenting was done in 24 cases (48%), 16 cases (32%) were having floating intimal flap; while the other 8 cases (16%) had residual stenosis > 30%. A primary patency rate of 92% was obtained by the end of the 12 months follow-up period. Conclusion: Duplex can be used as a first strategy for the treatment of femoropopliteal arterial diseases. However, the pitfalls in DGA technique make it insufficient to replace the classic fluoroscopy.

Background Many studies found association between psychosocial factors and suicidal behavior; this association differs from one community to another, and this difference could affect the risk assessment and the management of suicidal behavior. The aim of this work was to evaluate the role of socioeconomic, cultural, and psychosocial profile including psychiatric comorbidity on individuals with suicidal behavior who attended Tanta University emergency hospital. Results Family troubles were the commonest cause of suicidal behavior (28%), and drug overdose was the commonest method of attempt (38%). Positive correlation is between age and score of Beck scale for suicidal ideation (p = 0.000) which indicates that suicidal ideation increases with age. Significant association is between psychiatric comorbidity and Beck’s scale for suicidal ideation (p = 0.019), with size of association (η = 0.58). Regression analysis showed that older age, female sex, illiterates, widows, cases with psychiatric illness, and low socioeconomic status when act altogether are the significant predictor of suicidal ideation of our studied sample. Conclusions Our study demonstrated that studying psychosocial factors in individuals who came to emergency hospital of Tanta University could be a reflection of the community visiting this hospital asking for medical emergency service; the comprehensive and multifactorial assessment we have been adopted in this work could help in better understanding of the suicidal risk factors in this community and consequently help in part in tailoring the clinical service for this sector of patient.

Background: The utility of laboratory values to predict complications in pediatric burn                    patients is poorly understood. This study assessed the laboratory investigations’ role                              in morbidities and mortalities prediction after moderate and severe thermal burn in                    pediatrics. Methods: This prospective cohort study was carried out on 40 children with moderate                          and major thermal burn. All patients were subjected to clinical evaluation and laboratory investigations such as CBC, c-reactive protein (CRP), serum albumin, serum creatinine and             urea. Results: Patients were subdivided into two groups: uncomplicated group (n=25) and complicated group (n=15). CRP, serum albumin, platelet count, serum creatinine and urea can significantly predict sepsis incidence with AUC of 0.922, 0.912, 0.911, 0.807, 0.810, at cut off >12, ≤2, ≤194, >0.7, >23, with sensitivity of 100%, 90.91%, 100 %,100 %, 85.71%, specificity of 86.21 %, 86.21%, 79.31%, 24.24%, 39.39%, PPV of 73.3 %, 71.4%, 64.7%, 21.9% , 23.1% and NPV of 100 %, 96.2 %, 100 %, 100 % , 92.9% respectively. Serum creatinine and urea can significantly predict incidence of acute kidney injury (AKI) with AUC of 0.807, 0.810 At cut off >0.7, >23, with sensitivity of 100.00 %, 85.71%, specificity of 24.24%, 39.39%, PPV of 21.9%, 23.1% and NPV of 100.0%, 92.9% respectively. Percent of burn, total ABSI, CRP, platelet, inhalation injury, albumin, creatinine and urea were dependent predictors for mortality. Sex, inhalation injury, percent of burn, total ABSI, hemoglobin, CRP, platelet, albumin, and creatinine were dependent predictors for sepsis. Sex, inhalation injury, percent of burn, total ABSI, CRP, hemoglobin, platelet, albumin and creatinine were dependent predictors for complication of acute kidney disease. Conclusions: CRP, serum albumin, platelet count, serum creatinine and urea are good predictors of sepsis, AKI and mortalities after moderate to severe burn in pediatrics.