The present study focused on the beneficial effects of Lactococcus lactis subsp lactis CNRZ 1427 with possible use as a therapeutic agent against Sal-monella sp.; also we have proposed different therapeutic possibilities of our situation against a pathogen Salmonella sp. We have conducted two tests In Vitro and In Vivo; where it is noted that treatment in the presence of this lac-tic strain is effective since it causes a remarkable decrease of the pathogen agent. At the end, the effectiveness of this lactic strain was confirmed by testing for resistance to gastrointestinal conditions (pH, bile salts and diges-tive enzymes).
Within the framework of our research of medicinal plants a phytochemical and biological study of Asphodelus tenuifolius has been conducted. The study consisted of evaluating the antifungal activities of most of the chemical constituents extracted from leaves by many solvents and tested on Aspergil-lus flavus, A. parasiticus, A. ochraceus, A. fumigatus, A. niger, Penicillium expansum, Fusarium oxysporum and Alternaria sp.The inhibitory activity of phytochemicals was evaluated on fungi isolating from the imported France soft wheat marketed in Algeria, according to two methods: in agar medium and in Y.E.S. medium. The antifungal activity of the four extracts was evalu-ated against eight mycotoxicogenic fungi, by using agar dilution method. The phytochemical analysis conducted on A. tenuifolius leaves and roots re-vealed the presence of many compounds and the antifungal test results indi-cated a great potential of antifungal activity. Aspergillus species proved the most sensitive but F. oxysporum was the most resistance fungus. These re-sults explain that we can use A. tenuifolius as a natural antifungal agent to inhibit and to control mycotoxicogenic fungi.
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