An efficient and practical bis(pinacolato)diboron (B2pin2) mediated radical-radical cross-coupling of 4-cyanopyridine with aliphatic aldehydes/ketones has been established. The metal-free protocol features simple and mild reaction conditions, excellent functional group tolerance,...

The structural, dynamic, and vibrational properties during the heat transfer process in Si/Ge superlattices, are studied by analyzing the trajectories generated by the ab initio Car-Parrinello molecular dynamics simulation. The radial distribution functions and mean square displacements are

We have developed a borane-catalyzed sequential addition of terminal alkynes to para-substituted phenols, which affords a wide range of ortho-propargylic alkylated phenols bearing congested quaternary carbons. Control experiments combined with DFT calculations suggest that the reaction undergoes a sequential phenol alkenylation/hydroalkynylation process. Further extension of this strategy to the construction of triaryl-substituted quaternary carbons demonstrates the broad utility of this method.

Herein, we report the first intramolecular C−N bond formation of phenylpropanamide derivatives via organocatalytic oxidative reactions, affording 3,3-disubstituted oxindole derivatives with up to 99% yield. The high efficiency of this reaction is exemplified by the transition metal-free mild conditions and the ability to perform the reaction on a gram scale. Meanwhile, the DFT calculation of the catalytic oxidative transformation pathway has also been studied.O xindole scaffolds, especially 3,3-disubstituted oxindole derivatives, exist in many privileged natural products and biologically active compounds such as the alkaloid horsfiline, the antibacterial agent arundaphine, etc. (Figure 1). 1 Therefore, novel methods to obtain oxindoles are worthy of further investigation in synthetic organic chemistry.

Sila-isosteres have attracted increasing attention due to their potential application in a variety of fields and their different properties compared to their carbon-containing analogs. However, the preparation of these silicon-containing compound remains challenging and thus the development of alternative synthetic methodologies is desirable. Here, we employ B(C6F5)3 as catalyst to enable the synthesis of highly functionalized sila-benzoazoles via hydrosilylation and rearrangement cascade reaction of benzoazoles and commercially available silanes. This strategy also exhibits remarkable features such as 100% atom-economy, good functional group tolerance, broad substrate scope, easy scale-up and good catalytic performance, demonstrating its potential application in sila-isostere synthesis.