Flavin adenine dinucleotide (FAD) undergoes multisite
molecular recognition at the air-water interface
with mixed monolayers that are capable of complementary hydrogen
bonding. Molecular images were
obtained with an atomic force microscope (AFM) for mixed monolayers of
guanidinium (G) and orotate (O)
amphiphiles transferred from pure water and from aqueous FAD. The
AFM image of the G/O mixed
monolayer on FAD showed a periodic oblique pattern composed of two
kinds of methyl peaks with different
heights, whereas that on pure water showed a periodic hexagonal pattern
of only one kind of methyl peak.
The two-dimensional molecular patterning as height difference is
conceivably caused by rearrangement
of monolayer components based on specific recognition by the FAD
template molecule.
A monolayer of 2-amino-4,6-di(dodecylamino)-1,3,5triazine 1 transferred from barbituric acid solution onto a mica plate is observed by atomic force microscopy (AFM) to show regularly arrayed terminal methyl groups of 1 as a result of hydrogen-bond networking.We have recently reported multisite molecular recognition between multicomponent monolayers on water and flavin adenine dinucleotide (FAD) in water. 1 This result opened the possibility to control the alignment of component amphiphiles within a monolayer.2 We extended this concept one step further in the present study and examined extended hydrogen-bond network formation between a monolayer of 2-amino-4,6-di(dodecylamino)-l,3,5-triazine 17 and aqueous barbituric acid.
Molecular images for the mixed monolayers composed of guanidinium (G) and orotate (O) amphiphiles on pure water and on aqueous flavin adenine dinucleotide (FAD) solution were taken with an atomic force microscope (AFM). The AFM image of G/O mixed monolayer on FAD showed a periodic pattern composed of two kinds of peaks with different heights, whereas that on pure water showed a periodic peak. The molecular pattern is apparently induced by rearrangement of monolayer components based on specific recognition by FAD template molecule.
Electron diffraction studies of a [(dioctadecyl)carbamoylmethyl]guanidinium toluene-p-sulfonate (DG) monolayer reveal that the regularity of the molecular arrangement and the size of crystalline domains are controlled through binding of aqueous a,w-dicarboxylates with various spacer lengths.
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