The normal IS/OS junction observed in OCT3 images is associated with good visual recovery after MH closure. The presence of normal IS/OS junction may be important for visual recovery after MH repair.
Aim To determine whether significant correlations exist between retinal sensitivity measured by fundus-related microperimetry and the visual acuity and the foveal thickness measured by optical coherence tomography (OCT) in eyes with diabetic macular edema (DME). Methods A retrospective chart review of 32 eyes with DME and 17 normal healthy eyes that had undergone fundus-related microperimetry and OCT. The macular sensitivity was measured using the recently introduced fundus-related microperimeter, Micro Perimeter 1. The mean retinal sensitivities within the central 21 and 101 were correlated with the best-corrected visual acuity and OCT-measured foveal retinal thickness. Results The mean sensitivities in the central 21 and 101 were significantly lower in patients with DME than in normal subjects (Po0.0001). The mean retinal sensitivities in the central 21 and 101 were inversely correlated with visual acuity (r 2 ¼ 0.623, Po0.0001; r 2 ¼ 0.581, Po0.0001) and foveal thickness (r 2 ¼ 0.581, Po0.0001; r 2 ¼ 0.551, Po0.0001). Conclusions The mean retinal sensitivities measured with fundus-related microperimetry were significantly lower in eyes with DME than in normal eyes. Because a significant correlation of the microperimeter-determined retinal sensitivity to visual acuity and foveal thickness was observed, the retinal sensitivities obtained by fundus-related microperimetry may be another measure that can be used to assess the effects of DME.
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