sevoflurane and spike activity on ECoG and electroencephalography (EEG) [2,3]. Hypocapnea, which may be applied during neurosurgical procedures, also affects EEG spike activity [4,5]. Therefore, a combination of a high concentration of sevoflurane and controlled hyperventilation has been favored over other agents, because its use allows the induction of the epileptic seizure wave from cortical foci [6,7].We measured the effect of this anesthesia for epileptic cortical focus resection under ECoG on hemodynamics and hepatic and renal functions. Five consecutive patients (two male and three female) receiving epileptic cortical focus resections under ECoG underwent anesthesia with constant expiratory 2.5% sevoflurane with hyperventilation, at a partial pressure of arterial carbon dioxide (Pa CO2 ) of 30 mmHg. All patients were uneventfully extubated after the operation. The durations of anesthesia and the operation were 600 ± 216 (mean ±
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.