MDS is a common hematologic malignancy of the elderly, which places patients at risk for comorbid conditions. Transfusion dependency identifies patients with MDS at additional increased risk of organ impairment and shortened survival.
hypertension: $6,467, P < 0.001). Among patients developing CKD, all-cause mean [median] annualized costs increased significantly following CKD onset (increases for patients with diabetes: $8,829 [$4,899], P = 0.026; hypertension: $4,175 [$2,741], P = 0.004; diabetes and hypertension: $9,397 [$7,240], P < 0.001). In the post-CKD period, costs directly related to treatment of CKD accounted for 9%-19% of all-cause medical service costs-9.2% for patients with diabetes, 11.6% for patients with hypertension, and 18.8% for patients with both diabetes and hypertension.ConClusIon: CKD was associated with significantly higher all-cause health care costs in managed care patients with diabetes and/or hypertension.
ABSTRACTBACKgrounD: Diabetes and hypertension are the 2 major causes of endstage renal disease. The rate of chronic kidney disease (CKD) secondary to diabetes and/or hypertension is on the rise, and the related health care costs represent a significant economic burden.oBjeCTIve: To quantify from a health system perspective the incremental direct all-cause health care costs associated with a diagnosis of CKD in patients with diabetes and/or hypertension.
This study finds only 41% of ICT-eligible patients with lower-risk MDS received ICT in clinical practice, and treatment was initiated later than recommended. Receipt of ICT was associated with significantly longer survival.
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