5‐hydroxy‐γ‐lactams have been isolated as major byproducts from a classical 2‐aminopyrrole synthesis involving condensation of an in situ prepared α‐aminoketone with methyl cyanoacetate. The classical 2‐aminopyrrole was obtained in very low yield, or not at all. One 5‐hydroxy‐γ‐lactam was dehydrated to the known 5‐methylene‐γ‐lactam in good yield using thionyl chloride.
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