Background: PPIUCD is not commonly used in developing countries because of lack of awareness, social taboos and fear of complications of IUCD devices. Low acceptance of immediate PPIUCD usage results in high unmet needs and low utilization of the contraceptive method. Therefore we planned this study to see the acceptability and safety of PPIUCD in our local population. Material & Methods: A cross sectional, prospective study was conducted on 2540 women attending antenatal clinic at District hospital Samba, Jammu; Jammu and Kashmir from March 2016 to February 2018. All women attending antenatal clinic and in labour room were counseled for immediate PPIUCD and after written consent were included in the study. All these women were called for follow up visit after 6 weeks of insertion of PPIUCD. Results: A total of 2540 women were counseled for PPIUCD during their antenatal visits in third trimester and in early labour. Out of which 811 (31.9%) PP IUCD insertions were done. Most common age group was 26 -30 year. Most of PPIUCD insertions were done in vaginal deliveries i.e. 678(83.6%) out of 811 and intracesarean PPIUCD insertions were only 133(16.40%) out of 811. Most of the women were either Para 2 or Para 1. 396 (48.82%) women came for follow-up after 6 weeks. There was no case of uterine perforation or any unplanned pregnancy. Unusual vaginal discharge were reported by 76(19.19%) women at follow-up. In 32 women IUCD was removed because of heavy menstrual loss, PID and personal reasons. IUCD strings were not seen on per vaginum examination in 40(10.10%) cases. All women with undescended strings underwent ultrasonographic confirmation of intrauterine placement of the device and women were assured for continuation of PPIUCD. Conclusion:To achieve the goal of Health Services for all, all women should have access to family planning services. If family planning services are provided to all women then only we will be able to decrease maternal and infant mortality. Acceptance of PPIUCD as method of contraception is low, though PPIUCD is an effective, safe, rapidly reversible and convenient contraceptive method. PPIUCD should be encouraged considering the advantages that come along, although there is a relatively higher incidence of expulsions.

Tuberculoma is second only to neoplastic lesions as a cause of raised intracranial tension. Tuberculosis is quite common in developing countries. It is therefore quite likely that a pregnant patient with a history of convulsions may have tuberculoma. We had a similar case of term pregnancy with history of convulsions. CT scan clinched the diagnosis of tuberculoma. The patient delivered per vaginum. The patient was put on anti -tubercular drugs for 18 months and lesions disappeared on repeat CT.

OBJECTIVE:This study was designed to find out how socioeconomic, cultural, educational and religious factors play a role in causation of RTI/STD. STUDY DESIGN: This study was conducted at Gynae, OPD of Dist. Hospital Samba, Jammu, J&K. 200 patients coming for infertility checkup and treatment between Feb. 2013 to Jan. 2014 were included in the study. It was an observational cross -sectional study. A pretested, semi-structured questionnaire was administered which included information about demographic, socioeconomic profile, menstrual and sexual practices, obstetrics treatment and family history. Complaints suggestive of RTI/STI were noted. RESULTS: Maximum incidence of RTI/STI was observed in the age group 25 -30 years. RTI/STI was more in illiterate patients (64) as compared to literate patients (53 %). A negative correlation between income and prevalence of RTI was found. Prevalence of RTI was slightly more in patients from joint families (67%) as compared to women from nuclear families (33%). Similarly people living in Kutcha houses showed more prevalence of RTI (66%) as compared to pucca houses (48%). Correlation between RTI and housing was not significant (p > 0.005). Tap water supplied residents showed less prevalence of RTI 50% as compared to hand pump using residents 65%, however, correlation was not statistically significant (p > 0.05). The incidence of RTI was 54% in daily bathers and among irregular bathers, the incidence was 66%. The prevalence of RTI was 54%in regular wearers of underwear whereas in irregular wearers the prevalence was 75%. Genital hygiene correlation, the prevalence of RTI in pad users was 42.8% whereas the prevalence in non -pad users was 61%. There was statistically significant correlation between the use of rag during menses and the prevalence of RTI. RTI was more prevalent (64.8%) in women sharing toilets with others while same was 45.6% in women among having separate toilet facilities. CONCLUSION: RTI/STI is increasing worldwide. HIV and RTI/STI share the same mode of transmission and the persons suffering from STI/RTI practice the risk behavior which increases the probability of acquiring HIV. There is great need to develop strategies for awareness generation and management of these diseases.

Subacute Sclerosing Panencephalitis (SSPE) is a rare, chronic progressive demyelinating disease. Incidence of subacute sclerosing panencephalitis has declined after vaccination but annual incidence is quite high and in India its Incidence is 21 per million population. We had a case of term pregnancy with a history of forgetfulness, abnormal behaviour, abnormal movement of body and altered sensorium. Detailed history, neurologic examination, serology (CSF & serum) and MRI brain clinched the diagnosis. Patient underwent LSCS for fetal distress. She was put on trial of interferonalpha 2b but she developed superadded infection and died.

BACKGROUNDCarcinoma breast is a heterogenous disorder with varying clinical course and survival rates in same grade and stage of patients. Therefore, there is a need of classification system of carcinoma breast wherein the patients with similar clinical course and survival rates can be clubbed together in a subgroup. Molecular classification divides carcinoma into four categories based on ER/PR/HER-2/neu expression: ER+ and⁄or PR+ and HER-2/neu− (Luminal A), ER+ and⁄or PR+ and HER-2/neu+ (Luminal B), ER− and⁄or PR− and HER-2/neu+ (HER-2/neu overexpressing), ER−, PR− and HER-2/neu− (Triple negative/Basal like). This classification has prognostic and predictive value and allows personalised, molecular targeted therapy. There is a geographical difference in the prevalence of these molecular subtypes, similar to the incidence of carcinoma breast.The aim of our study is to classify and define precisely the prevalence of molecular subtypes of carcinoma breast in our population using ER, PR and HER-2/neu immunohistochemistry on formalin-fixed paraffin-embedded blocks and to correlate these subtypes with histological and clinical features. The objective of our study is to evaluate the prevalence of molecular subtypes of carcinoma breast in our Population. MATERIALS AND METHODSIt was an observational study wherein all cases of carcinoma breast from January 2010 to Dec. 2016 were retrieved, reviewed, graded and staged according to the 2003 WHO histological classification of breast tumours. Immunohistochemistry was for oestrogen receptor (ER), progesterone receptor (PR) and HER-2/neu was done in those cases where there was clinical requisition. Statistical analysis and correlation among categorical variables in the univariate analysis were determined using the Pearson-ChiSquare test. Significance was assumed at p -value less than 0.05. RESULTS Of total 40 cases, ER CONCLUSIONThe carcinoma breast is a heterogenous disorder clinically, morphologically and molecularly. Increasing number of molecular subtypes are being described which have prognostic and predictive value. Thus, emerging evidence shows promise that traditional classification of carcinoma breast can be supplemented with molecular classification for specialised, personalised and molecular targeted therapy. KEYWORDSCarcinoma Breast, Molecular Classification, Immunohistochemistry, Oestrogen Receptor, Progesterone Receptor, HER-2/neu. HOW TO CITE THIS ARTICLE: Atri SK, Rana VM, Rana M, et al. Prevalence of molecular subtypes of carcinoma of breast-A study from North India. J. Evolution Med. Dent. Sci. 2017;6(89):6204-6207, DOI: 10.14260/jemds/2017/1349 BACKGROUND Carcinoma breast is the most common malignant neoplasm in females and second most common malignant neoplasm worldwide. 1 The incidence of carcinoma breast is progressively increasing over last decades 2,3 and especially in India where carcinoma breast is now most common malignant neoplasm 'Financial or Other Competing Interest': None. Submission 07-10-2017, Peer Review 31-10-2017, Acceptance 03...