Stress is a kind of physical or psychological exhaustion caused by actual or superficial problems. When pressures in working environment build up, a considerable impact on body and mind can be developed. This condition may lead the worker in to a harmful accident and bring about a dangerous situation. In many countries forestry is one of the toughest and most difficult types of occupation. Working in forest is intensive and involves a high degree of risk. Operating chainsaw and skidder are known as two most stressful occupations in forest. In order to study effect of occupational stress on mental health of forest workers, a research was conducted on the workers of two companies Mazandaran Wood and Paper Manufactory and Nekachoob Wood Technology using GHQ-28 questionnaire (General Health Questionnaire). Furthermore, in order to investigate and compare forest workers under impact with greater details, control group was also considered. Kroskal-Wallis test showed that there was a significant difference between target and contro groups in terms of mental health at 99 percent statistical levels. Working conditions and occupational stress had negative impact on mental health of both chainsaw and skidder operators so seriously that they showed symptoms like anxiety, nervousness, lack of sleep, etc.

BackgroundThe mother’s consumption of high-fat food can affect glucose metabolism and the hypothalamic–pituitary–adrenal axis responsiveness in the offspring and potentially affect the metabolic responses to stress as well. This study examines the effect of maternal high-fat diet on the expression of pancreatic glucose transporter 2 and the secretion of insulin in response to stress in offspring.MethodsFemale rats were randomly divided into normal and high-fat diet groups and were fed in accordance with their given diets from pre-pregnancy to the end of lactation. The offspring were divided into control (NC and HFC) and stress (NS and HFS) groups based on their mothers’ diet and exposure to stress in adulthood. After the two-week stress induction period was over, an intraperitoneal glucose tolerance test (IPGTT) was performed and plasma glucose and insulin levels were assessed. The pancreas was then removed for measuring insulin secretion from the isolated islets as well as glucose transporter 2 mRNA expression and protein levels.ResultsAccording to the results obtained, plasma corticosterone concentrations increased significantly on days 1 and 14 of the stress induction period and were lower on the last day compared to on the first day. In both the NS and HFS groups, stress reduced plasma insulin concentration in the IPGTT without changing the plasma glucose concentration, suggesting an increased insulin sensitivity in the NS and HFS groups, although more markedly in the latter. Stress reduced insulin secretion (at high glucose concentrations) and increased glucose transporter 2 mRNA and protein expression, especially in the HFS group.ConclusionMothers’ high-fat diet appears to intensify the stress response by changing the programming of the neuroendocrine system in the offspring.

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Based on the results of present study, miR-451/IL-8 pathway is a possible mechanism for hepatoprotective action of trans-chalcone in long-term.