Pituitary adenoma most frequently is the cause of hypopituitarism occurring in adult life. However, a pituitary cyst, with certain distinctive histologic features pointing to an origin from Rathke's cleft, may be the pathologic cause. The rarity of this condition is evidenced by the paucity of published reports. 6-s 12,14 Some of the patients, in the reported cases, had signs of hypopituitarism, others had a predominance of effects of pressure on nearby structures. The incidental finding, post mortem, of such a cyst, in an elderly man who clinically had presented signs of myocardial infarction and hypopituitarism, warranted this report. It deals with the embryologie and morpho]ogie aspects of the cyst together with the clinical and laboratory findings.
Mucin‐producing carcinoma of the female breast was studied by histochemistry, electron microscopy and tissue culture. The tumor cells and lakes of secretion contained strong and weak acidic mucins. Weakly acidic mucins were abundant in areas of adjacent atypical intraductal hyperplasia. Mucin production in the benign atrophic areas was scanty and mainly of the neutral variety. Electron microscopy revealed elaborate organelle morphology as compared to the simple structure of the more common infiltrating duct carcinoma. In cell culture the tumor cells proliferated and produced mucin for 6 weeks through 2 subcultures.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.