The dental pulp is a specialized tissue formed by connective tissue surrounded by mineralized dental tissues. 1 Its vitality and sensibility are established by the presence of the vascular-nervous bundle, which nourishes the pulp through the apical foramen. 2 When exposed to an aggressor agent, the pulp can present inflammatory or degenerative reactions that depend on the type, frequency and intensity of the irritating stimulus. 1 Local factors such as mechanical stimuli produced by orthodontic movement can stimulate a series of morphological and functional changes in the oral cavity. For example, dental anchorage may cause
This study aimed to analyze part of the financial resources used to fund public health actions in the 26-Brazilian capitals, from 2008 to 2018. This is a time-trend ecological study involving revenue and expenditure indicators provided by the Information System on Public Budget for Health (SIOPS). The values were deflated based on the Extended National Consumer Price Index of 2018 in Brazil to allow the comparison over the years. The mean annual variation of health investments, in Brazilian Reais (BRL) was assessed using linear regressions. Pearson’s correlation coefficients were estimated between federal revenues and expenditures with the capitals’ resources. All capitals presented statistically significant positive correlations for the origin of the budget resource invested in health. The lowest coefficient was found in the capital city of Macapá (Amapá State) (r = 0.860) and the highest, in Fortaleza (Ceará State) (r = 0.997). Belo Horizonte (Minas Gerais State) was the capital with the highest annual increase in federal transfers (about BRL 67.91 per year) and Teresina (Piauí State) presented the highest annual increase in health expenditures among the capitals (about BRL 55.42 per year). We found a increase in the transfers of the Brazilian Unified National Health System (SUS) and municipal resources in almost all capitals, but there are still inequalities in the distribution of financial resources among Brazilian capitals from different regions. Health funding is affected by the municipalization of SUS and it is not the single factor affecting the access and quality of health services.
Objetivo: Avaliar o padrão de herança queiloscópico, transmitido de mãe para filha, e sua aplicabilidade na identificação humana. Metodologia: Tratou-se de um estudo transversal de natureza qualitativa e quantitativa, elaborado de acordo com o Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). A amostra foi composta por 30 acadêmicas de Odontologia da Universidade Estadual de Feira de Santana (UEFS), e suas respectivas mães. O método consistiu em três etapas: mensuração da espessura labial, classificação das comissuras dos lábios e avaliação do padrão sulcular, seguindo a classificação de Suzuki e Tsuchihashi. Os dados foram analisados estatisticamente utilizando testes Qui-quadrado de Pearson e Exato de Fisher. Resultados: As características labiais mais prevalentes foram a presença de lábios mistos, grossos/muito grossos e da comissura labial disposta horizontalmente. Na avaliação do padrão sulcular prevaleceram os sulcos tipo I (linhas verticais completas) e I’ (linhas verticais incompletas). A espessura e o tipo de comissura labial apresentaram maior potencial de transmissão de mãe para filhas, quando comparado aos tipos de sulcos labiais. Conclusão: A análise dos lábios evidenciou algumas características que apresentam maior semelhança entre mães e filhas, sendo o padrão das impressões labiais a característica de menor semelhança entre os descendentes estudados.
Background Chloroquine and hydroxychloroquine are 2 medications used to treat some systemic diseases.Objective The aim of this scoping review was to assess the occurrence of oral pigmentation induced by chloroquine or hydroxychloroquine and to understand the pathogenic mechanism behind this phenomenon. MethodsThe review was performed according to the list of PRISMA SrC recommendations and the JBI Manual for Evidence Synthesis for Scoping Reviews. MEDLINE (PubMed), Scopus, EMBASE, SciELO, Web of Science, Lilacs, and LIVIVO were primary sources, and "gray literature" was searched in OpenThesis and Open Access Thesis and Dissertations (OATD). Studies that screened the occurrence of oral pigmentation associated to the use of chloroquine or hydroxychloroquine were considered eligible. No restrictions of year and language of publication were applied. Study selection and data extraction were performed by 2 independent reviewers. The risk of bias was assessed through the JBI tool, depending on the design of the selected studies. ResultsThe initial search resulted in 2238 studies, of which 19 were eligible. Sixteen studies were case reports, 2 had case-control design and 1 was cross-sectional. Throughout the studies, 44 cases of oral pigmentation were reported. The hard palate was the anatomic region most affected with pigmentation (66%). According to the case reports, most of the lesions (44%) were bluish-gray. The minimum time from the beginning of treatment (chloroquine or hydroxychloroquine) to the occurrence of pigmentation was 6 months. The mean treatment time with the medications was 4.9 years, and the mean drug dosage was 244 mg. Most of the studies (63.1%) had low risk of bias (high methodological quality).Conclusions The outcomes of this study suggest that hyperpigmentation depend on drug dosage and treatment length. Hyperpigmentation was detected after a long period of treatment with chloroquine or hydroxychloroquine.
Objetivo: Avaliar as condições de saúde bucal de dependentes químicos em processo de recuperação do município de Rio Verde - Goiás. Metodologia: Foi realizado um estudo transversal descritivo, de acordo com as recomendações do Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). Foram analisados 41 questionários de saúde pertencentes a 24 homens e 17 mulheres, pacientes de duas comunidades terapêuticas do município de Rio Verde-Goiás, com faixa etária predominante de 31 a 40 anos. Dados da anamnese, exame clínico intrabucal, índice CPO-D, índice periodontal comunitário e índice de placa corada foram analisados. Os resultados foram expressos por meio de estatística descritiva. Resultados: O CPO-D médio da população em estudo foi de 14,72. Pouco mais da metade dos indivíduos, 53,65% (n=22), apresentaram sangramento à sondagem. A higiene bucal de 75,61% (n=31) foi considerada precária e 48,78% (n=20) relataram não fazer uso diário do fio dental. Lesões em mucosa oral esteve presente em 39,02% (n=16) dos pacientes avaliados. Conclusão: De acordo com os resultados obtidos, observou-se condição de saúde bucal desfavorável entre os participantes do estudo, demonstrando a importância da elaboração e emprego de estratégias educativo-preventivas à população de dependentes químicos em processo de recuperação.
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