It could be postulated that biological influence on sexual behaviour is powerful and resistant to the influence of time and place, as well as socio-cultural religious influences. A high rate of premarital sexual activity with a number of sexual partners, a relatively low rate of condom use and the fact that 4% of the female adolescents in this sample had an induced abortion suggest that there are gaps in the education provided to adolescents about sexual and reproductive risks within the Serbian speaking territory. An alarming statistic is that 5% of the female adolescents in this sample reported that they had been raped, or forced to participate in non-consensual sex within an ongoing relationship with a regular partner. There is a need for systemic changes within the field of sexual education and protection from sexually risky behaviour among young adults.

Background/Aim: Multiple sclerosis is a disease whose aetiology involves multifactorial interactions among genetic and environmental factors. Obesity is one of the most important environmental factors conducive to the onset and progression of the disease. The aim of the study was to determine the value of body mass index (BMI) in a population of patients with multiple sclerosis compared to the general population, in order to assess the relation between the BMI and physical disability in patients with multiple sclerosis and the influence of the BMI on the course and progression of the disease. Methods: A cross-sectional study was performed in 100 patients suffering from multiple sclerosis (experimental group) and 50 healthy people (control group). In order to determine the degree of physical disability, the Expanded Disability Status Scale (EDSS) was used. Clinical and demographic data and values of the BMI in both studied groups were collected. Statistical analysis included the descriptive statistics, t-test, chi-square test, analysis of variance, correlation and regression analysis. Results: Mean body weight and BMI were significantly higher in the control group (p< 0.05). There was no significant correlation between EDSS and BMI (p = 0.574). There was a correlation between the course of MS and the fact whether BMI was abnormal or normal (p = 0.031). Conclusion: BMI is an environmental factor that significantly correlates with the progression and prediction of multiple sclerosis, but not to the degree of physical disability.

Stroke is the most frequent neurological disorder, and the most common cause of severe disability compared to other diseases. Recombinant tissue plasminogen activator (rt-PA) is the only approved specific therapy for acute ischemic stroke. Hemorrhage is a significant complication of thrombolytic treatment. This study, which included a hundred patients (52 male and 48 female), was aimed at assessing the safety according to our experience with 100 thrombolytic treatments for stroke. The death rate related to hemorrhage after thrombolysis was 3%. The frequency of hemorrhagic events (hemorrhagic infarctions type 1 and 2, parenchymal hematomas type 1 and 2) was 16%. The study results have shown that the intravenous recombinant tissue plasminogen activator (rt-PA) therapy is safe.

AbstractThe aim of this study was to examine the effect of treatment type on anxiety in patients with cervical cancer. Subjects and methods: This prospective study was conducted in 60 patients with cervical cancer treated by radiotherapy. The study was done before treatment, and 3 and 6 months after initial testing. For assessment of anxiety the Hamilton Anxiety Scale (HAM-A) was used.: At baseline, the values of the scale of anxiety in patients who were treated surgically were significantly higher than in patients who had been treated by radiotherapy, but the intensity of anxiety gradually decreased in both groups. In this study, pain and irregular menstrual bleeding were the most important risk factors for the development of anxiety.: Routine assessment should be introduced in clinical practice for the detection and monitoring of anxiety in all patients with cervical cancer, and a psychiatrist should be included in the multidisciplinary team for their treatment.

Introduction: Etiology of multiple sclerosis (MS) involves multi-factorial interactions among genetic and environmental factors. Cigarette smoking is one of the most important environmental factors that increase the disease risk by about 50%. The aim of this research was to assess the prevalence of smoking in MS patients compared to the general population, and to assess the association between smoking and physical disability in MS patients. Materials and Methods: A cross-sectional study included 100 MS patients and 50 healthy people. For estimation of the degree of physical disability, the Expanded Disability Status Scale (EDSS) was used, and for clinical and demographic data a general questionnaire was used. In order to collect data on the smoking, the questionnaire for examining risk factors for vascular disease among patients with MS was used. Results: Analysis of smoking incidence showed that, between MS and control group, smoking was a dependent variable (2 = 6.258, p = 0.04). There was no statistically significant difference in the number of cigarettes, nor in the duration of smoking. There was no significant correlation between smoking in MS group and the index of disease progression (r=0.216, p=0.133). Also, the relationship between EDSS and smoking had no statistical significance, as well as between the disease course and smoking (2 = 1.531, p = 0.216). Conclusion: Although it seems reasonable to restrict or refrain from smoking in patients with MS there was no significant evidence of smoking and disease progression correlation.

Cerebrovascular diseases represent a serious global health problem. They are the leading cause of disability and second cause of death worldwide. Identification of risk factors and early diagnosis allow prompt prevention and treatment. Group of authors, through a case report of a patient with a symptomatic internal carotid artery occlusion and an overview of diagnostic and therapeutic protocol, alludes to the advantages of ultrasonographic diagnosis not only with diagnosis itself but with the subsequent patient's follow-up. Ultrasonographic diagnosis is completely sufficient with respect to more expensive and invasive diagnostic procedures and it provides a complete insight of brain circulation in real time. When it comes to the assessment of collateral brain circulation, ultrasonographic diagnosis is the method of choice.

Introduction: Stroke is one of the most severe and the most common diseases of modern man. Prevention is necessary in order to detect people who have risk factors for it. Objective: To determine the frequency of asymptomatic carotid disease in people of different ages. Subjects and methods: The project encompassed the part of population, that is, groups at high risk for stroke from the Republic of Srpska. 20 240 patients were examined-there were 12797 (63.23%) females and 7443 (36.77%) males. The study protocol was created, as well as adequate software products to support all phases of project implementation such as preparation of marketing materials, doctors' appointments, building of application for doctors and nurses to record patients' data, reports, analysis and conclusion. Upon completion of the project, data were statistically processed and the analysis of obtained results was conducted. Discussion: Pathological changes in blood vessels were noticed through the ultrasound examination of the aforementioned blood vessels of the neck and head, and the degree of narrowing of the blood vessels was determined. Furthermore, adequate measures and treatment to prevent progression of the aforementioned as well as the occurrence of stroke were applied. On the basis of the obtained data, it was concluded that the age was one of the most significant predisposing factors for the development of asymptomatic carotid disease. It was also noted that females were, more than men, prone to developing carotid asymptomatic disease. Conclusion: Average stenosis of all respondents was 18.36% (in females, stenosis was approximately 3.92% lower and it was 16.92%, when compared to males-20.84%). Overall median was 16% (in females 15% and it was 5% lower than in men-20%).

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