SUMMARYIntroduction: Modern way of life contributes to the ever increasing incidence of atherosclerosis and associated cardiovascular disease. Accordingly, prescribing of statins, drugs used for primary and secondary prevention of cardiovascular events, gains momentum worldwide. The aim of this study was to analyze profi le of drug dispensing, side eff ects frequency and correlation with treatment duration. Subjects and methods:The study included 44 randomly selected patients who used statins. The length of the follow-up was a one month, in the outpatient pharmacy situated in the city of Belgrade, where patients fi lled out the survey. Data were statistically analyzed and presented in tables and graph enclosed. Results: PResults showed that it is more frequent use of these drugs in secondary prevention of cardiovascular events, than in primary. Likewise, there is a signifi cant diff erence in distribution between diff erent therapy duration categories and indication (χ 2 = 7.726; p = 0.021) and signifi cant diff erence in distribution between diff erent categories in weight gain (χ 2 =11.535; p=0.003). The average ages of respondents were 66.93±7.65 years, and average duration of therapy 31.68 months. Conclusion: Based on the results, it can be concluded that the use of statins is justifi ed in primary prevention up to 32 months of duration. After this period additional measures concerning its justifi cation are required. From the standpoint of pharmacovigilance, it is necessary to frequently conduct the evaluation of prescriptions and use of these drugs, in order to prevent side eff ects.
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