A new rhodium(I) catalyst allows practical and efficient alkyne carbothiolation reactions to be achieved on synthetically useful ketone-bearing aryl methyl sulfides. The carbothiolation adducts, featuring a ‘recycled methyl sulfide’ activating group, are convenient precursors to highly substituted isoquinolines.
A rhodium(i) catalyst mediates selective and efficient coupling reactions between arylmethylsulfides and terminal alkynes to provide Sonogashira-like products.
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