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The Rashba effect in several surface systems, Au(111), Au(110), Ag(111), Sb(111) and Si(111)-Bi, is studied by means of first-principles relativistic density-functional calculations. The importance of the asymmetric behavior around the surface atom is emphasized as a crucial factor to determine the magnitude of Rashba spin splitting in addition to the size of the spin-orbit coupling. The Rashba effect at the Brillouin-zone boundary is generally described with time-reversal symmetry. Distinctive features in the spin splitting and spin direction for a two-dimensional hexagonal system are discussed with the use of symmetry in the double group of k.

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We experienced 12 cases of congenital cystic adenomatoid malformation of the lung (CCAM) including 6 cases diagnosed antenatally. They were classified into three groups according to the clinical manifestations. Group A was associated with hydrops fetalis (n = 3), group B presented with respiratory distress symptoms after birth (n = 6), and group C showed no respiratory symptoms (n = 3). All cases of group A were lost because of hydrops and respiratory failure due to pulmonary hypoplasia. Because a compression of the mass is thought to be a cause of hydrops, this group is considered to be a good indication for fetal treatment. All cases of group B showed progressive respiratory symptoms a few days after birth which were successfully treated surgically. In 2 of 3 cases of group C, the lesions decreased in size both antenatally and postnatally. We conclude that serial sonographic evaluations for fetal CCAM are important. If the fetus develops hydrops, fetal surgery is to be considered. If not, however, fetal surgery should not be done, because some lesions can shrink in size, or even disappear, while others can be treated successfully after birth by lobectomy or even segmentectomy.

Patients should be carefully monitored when receiving long-term parenteral nutrition including manganese, even when the manganese dose is small and the frequency of receiving a manganese supplement is low.

We therefore need to pay more attention to these problems when treating this disease in order to improve the overall prognosis significantly.

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