The interactions between sodium dodecyl-and tetradecylsulfates or sodium alkylbenzenesulfonate and a copolymer of N-vinylpyrrolidone with vinylamine (9 : I by mole) in aqueous solution were investigated by polarized luminescence. Polymer complexes of these anionic detergents with the copolymer were obtained and their antimicrobial and toxic properties as well as their effect on a bacterial enzyme, penicillinase, were investigated. It was found that these polymer complexes do not disintegrate on passing from aqueous to salt solutions, are 4 to 5 times less toxic than the initial anionic detergents and are comparable to the latter in both their antimicrobial activity and the ability for inhibiting penicillinase.

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