This paper deals with 2 female cases, aged 21 and 17, diagnosed as the Romano-Ward syndrome. They belonged to different families. Both showed autosomal dominant inheritant traits. From their traits one case (Case 1) was suspected as being in the heterozygous state, while the other (Case 2) in the homozygous. The severity in clinical symptoms did not differ from each other. By studying our cases and the literature so far published, the combined use of propranolol, diphenylhydantoin, and phenobarbital was inferred to act effectively for the prevention of arrhythmias seen in the present syndrome.
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