See Maass and Shine (doi: ) for a scientific commentary on this article. Entorhinal cortex is affected early in Alzheimer’s disease and is critical for navigation. Using immersive virtual reality, Howett et al. reveal navigational deficits in biomarker-positive patients with mild cognitive impairment. Navigational deficits are more sensitive and specific to Alzheimer’s disease risk than a battery of reference cognitive tests.

This article presents three methods to forecast accurately the amount of traffic in TCP=IP based networks: a novel neural network ensemble approach and two important adapted time series methods (ARIMA and Holt-Winters). In order to assess their accuracy, several experiments were held using real-world data from two large Internet service providers. In addition, different time scales (5 min, 1 h and 1 day) and distinct forecasting lookaheads were analysed. The experiments with the neural ensemble achieved the best results for 5 min and hourly data, while the Holt-Winters is the best option for the daily forecasts. This research opens possibilities for the development of more efficient traffic engineering and anomaly detection tools, which will result in financial gains from better network resource management.

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Abstract-Comparing graphs to determine the level of underlying structural similarity between them is a widely encountered problem in computer science. It is particularly relevant to the study of Internet topologies, such as the generation of synthetic topologies to represent the Internet's AS topology. We derive a new metric that enables exactly such a structural comparison, the weighted spectral distribution. We then apply this metric to three aspects of the study of the Internet's AS topology. (i) we use it to quantify the effect of changing the mixing properties of a simple synthetic network generator. (ii) we use this quantitative understanding to examine the evolution of the Internet's AS topology over approximately 7 years, finding that the distinction between the Internet core and periphery has blurred over time.(iii) we use the metric to derive optimal parameterizations of several widely used AS topology generators with respect to a large-scale measurement of the real AS topology.

The forecast of Internet traffic is an important issue that has received few attention from the computer networks field. By improving this task, efficient traffic engineering and anomaly detection tools can be created, resulting in economic gains from better resource management. This paper presents a Neural Network Ensemble (NNE) for the prediction of TCP/IP traffic using a Time Series Forecasting (TSF) point of view. Several experiments were devised by considering real-world data from two large Internet Service Providers. In addition, different time scales (e.g. every five minutes and hourly) and forecasting horizons were analyzed. Overall, the NNE approach is competitive when compared with other TSF methods (e.g. Holt-Winters and ARIMA).Paulo Cortez is with the