(1) Background: Stress, anxiety, and depression have been identified as factors that influence the development of inflammatory bowel disease (IBD). The main aim of this study was to test the effectiveness of group multicomponent cognitive-behavioral therapy at reducing stress, anxiety, and depression, and improving quality of life and the clinical course of the disease. (2) Methods: A total of 120 patients were evaluated using the General Perceived Stress Scale, Scale of Stress Perceived by the Disease, the anxiety and depression scale, and quality of life questionnaire for patients with IBD. Disease activity was measured using the Mayo Index for ulcerative colitis and CDAI for Crohn's disease, as well as the number of relapses self-reported by patients. Patients were randomized to receive group multicomponent cognitive-behavioral therapy or treatment as usual. (3) Results: The psychological intervention reduced stress (EAE: 45.7 ± 8.8 vs. 40.6 ± 8.4, p = 0.0001; PSS: 28.0 ± 7.3 vs. 25.1 ± 5.9, p = 0.001) and improved quality of life (164.2 ± 34.3 vs. 176.2 ± 28.0, p = 0.001). An improvement was found in the number of relapses self-reported by patients (0.2 relapses/patient vs. control 0.7 relapses/patient; p = 0.027). No differences were found in disease activity indexes. (4) Conclusions: Psychological therapy was associated with improved stress, quality of life and with a decrease in the number of relapses self-reported by patients. Clinical trial registration number: NCT02614014

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Theoretical Framework: The goal of this study is to evaluate the effectiveness of a group intervention program in chronic pain. Methods: The sample consists of 42 participants, patients of the Pain Unit at the General University Hospital of Alicante. Only 30 completed the study. Subjects voluntarily completed a battery of questionnaires before and after the application of the program. In the study were measured the pain level as dependent variable and as independent variables the quality of life, anxiety, depression, sleep architecture and selfefficacy. Results: The program evaluation results show some improvements in almost all variables, and also differences in the effectiveness of the program between chronic pain patients and fibromyalgia patients. Conclusion: From the results we can conclude that both clinical entities are equivalent but respond in a different way because they are based on medical conditions with different intensity.

Variables emocionales y calidad de vida en pacientes en tratamiento de hemodiálisis Emotional variables and Quality of Life in patients with hemodialysis

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