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Topical vancomycin applied to the sternal edges, in conjunction with perioperative antibiotics and tight glycemic control, helps to eliminate wound infections in cardiac surgical patients.

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This is a case of aortic valve endocarditis and leaflet perforation caused by Staphylococcus lugdunensis successfully treated with aortic valve replacement and antibiotics. We believe that the patient's endocarditis may be related to the vasectomy he underwent two months prior to presentation, as S. lugdunensis is an integral component of normal skin flora of the lower abdomen and groin. We also suggest that whenever this organism is found in patients with endocarditis, early surgical treatment of the infected valve should be considered, as S. lugdunensis is an aggressive and virulent coagulase-negative staphylococcus.

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Carotid stenosis is a frequent coexisting condition in patients undergoing coronary artery bypass graft (CABG) surgery. The impact of carotid stenosis on cerebral perfusion is not fully understood. The purpose of this study was to determine the impact of carotid stenosis on cerebral blood flow velocity in patients undergoing CABG. Seventy-three patients undergoing CABG were prospectively recruited and underwent preoperative Duplex carotid ultrasound to evaluate the degree of carotid stenosis. Intraoperatively, transcranial Doppler ultrasound was used to record of the mean flow velocity within the bilateral middle cerebral arteries. Additionally, during the period of cardiopulmonary bypass, regulators of cerebral hemodynamics such as hematocrit, partial pressure of carbon dioxide, and temperature were recorded. The ipsilateral middle cerebral artery mean flow velocity was compared in arteries with and without carotid stenosis using a repeated measures analysis. Seventy-three patients underwent intraoperative monitoring during CABG and 30% (n=22) had carotid stenosis. Overall, MFV rose throughout the duration of CABG including when the patient was on cardiopulmonary bypass. However, there was no significant MFV difference between those arteries with and without stenosis (F=1.2, p=.21). Further analysis during cardiopulmonary bypass, demonstrated that hemodilution and partial pressure of carbon dioxide may play a role in cerebral Contact Author (and reprints): James L. Rudolph, VABHS GRECC (JP-182),