Ehlers-Danlos syndrome is a group of hereditary disorders characterized by alterations in the connective tissue manifested by hypermobility in joints, hyperextensible skin, and fragility associated with respiratory, cardiovascular, digestive, and musculoskeletal disorders. It is necessary to perform a differential diagnosis with hereditary connective tissue diseases such as Marfan syndrome, Larsen, cutis laxa and osteogenesis imperfecta[1]. In the syndrome there is a group of connective tissue disorders, characterized by hyperextensible skin, joint hypermobility, skin disorders, fatigue, chronic pain, cardiovascular, bone, neurological, spinal, psychological, gastrointestinal and respiratory disorders. There are 14 subtypes in the international classification of Ehlers-Danlos syndrome, with the hypermobile subtype being the most common [2]. Intubation difficulties can arise secondary to the collapse of fibroelastic tissues in the trachea, as well as affecting the tissues of the larynx and skin, cervical instability presenting a set of anesthetic challenges. It is associated with obstetric complications such as threatened abortion, spontaneous abortions, premature delivery and premature rupture of membranes [3]. We present the case of a 28-year-old patient with Ehlers-Danlos syndrome with a pregnancy of 35.6 weeks associated with preeclampsia with severity criteria and probable abruption of a normoinserted placenta, managed urgently in our hospital unit, resolving without complications.