Primary squamous cell carcinoma (SCC) associated with ovarian endometriosis is extremely rare and has a poor prognosis due to insufficient information on the optimal postoperative treatment. Here, we describe the response of this tumor to the administration of paclitaxel-carboplatin. A 45-year-old woman diagnosed with stage IIIc primary SCC of the ovary associated with endometriosis underwent optimal surgery followed by six courses of chemotherapy at 3-week intervals with paclitaxel and carboplatin. She tolerated the chemotherapy well and remained without evidence of disease during first-line chemotherapy. Two months later, she was readmitted with recurrence of a pelvic tumor. Although she was treated with chemotherapy (weekly paclitaxel and chemotherapeutic regimen of irinotecan + mitomycin C), the tumor was resistant to second-line and third-line chemotherapy and she died 15 months after surgery. Paclitaxel-carboplatin administration may be an effective treatment for primary SCC of the ovary but further studies are required to investigate it true efficacy in the treatment of this disease.
Parasitic leiomyoma is a rare manifestation of uterine leiomyoma that loses its adherence to the uterus to attach to other pelvic or intra-abdominal organs. Most reported tumors presented during laparoscopic myomectomy or hysterectomy.We report here a case of spontaneous parasitic leiomyoma with torsion in a 30-year-old woman with no previous surgeries. She was diagnosed with a subserosal leiomyoma during pregnancy. She reported pain during her second trimester because of the leiomyoma, which disappeared with conservative treatment, and she eventually delivered at full-term. After 2 years, she opted for surgical removal of the leiomyoma. Through preoperative transvaginal ultrasonography, we suggested the tumor to be ovarian in origin because it was located far from the uterus.Laparoscopy revealed the tumor to be separated from the uterus with a 720° torsion on the vesicouterine pouch.A postoperative histopathological examination diagnosed the tumor as a parasitic leiomyoma. There have only been 24 reports of spontaneous parasitic leiomyoma, and this is the first case with associated torsion in Japan. We believe that we have experienced an extremely rare case of leiomyoma.
Objective: We aimed to clarify the trends in outcomes of various types of hysterectomy in our hospital. We also assessed the factors that influenced operating time and intraoperative blood loss in patients who underwent hysterectomy. Design: We conducted a retrospective study and evaluated a total of 293 patients who underwent abdominal or laparoscopic hysterectomy between 2008 and 2013. Main Outcome and Measure(s): We measured operating time, intraoperative blood loss, uterine weight, and surgical complications. Result(s): The proportion of total laparoscopic hysterectomy (TLH) performed has been increasing in recent years. In 2013, TLH accounted for 72.9% of all cases of hysterectomy in our facility. Fourteen of 152 patients (9.2%) in our study who underwent laparoscopic surgery required conversion to laparotomy. Median operating time in TLH was significantly longer than in laparoscopically assisted vaginal hysterectomy (LAVH) and abdominal total hysterectomy (ATH). Median intraoperative blood loss was significantly lower in TLH than in LAVH and ATH. Median weight of the uterus removed by ATH was greater than that removed by LAVH and TLH. In laparoscopic hysterectomy, there was a positive correlation between uterine weight and operating time. Intraoperative complications occurred in two LAVH patients and in four TLH patients. Postoperative complications in the TLH group included two cases of uretero-vaginal fistula and one case of hematoma of the vaginal cuff. Postoperative complications occurred in four cases in the ATH group. Conclusion(s): Our clinical proficiency with TLH is increasing, and we believe that continued experience and technical improvements in laparoscopic hysterectomy will lead to improved safety and effectiveness of the procedure.
An ovarian carcinoid tumor is extremely rare; the incidence is about 1.3% of all carcinoid tumors. A case of a primary ovarian carcinoid tumor with a mature cystic teratoma diagnosed after laparoscopic surgery is presented. The patient is a 35-year-old gravida 2, para 2 who was diagnosed with a left ovarian tumor during her second pregnancy. Magnetic resonance imaging (MRI) revealed a mature cystic teratoma. In the third postpartum month, she underwent a laparoscopic assisted ovarian cystectomy. The pathological examination revealed that most of the tumor was a mature cystic teratoma, including a small focal lesion of insular carcinoid tumor, which showed a positive reaction with chromogranin-A. Therefore, a laparoscopic left salpingo-oophorectomy was performed. Although the prognosis of this tumor is favorable, careful periodic examinations might be necessary because a small number of cases can recur.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.