Abstract:As the scope of nanotechnology applications in medicine evolves, it is important to simultaneously recognize and advance contributions germane to public health. A wide range of innovations in nanomedicine stand to impact nearly every medical specialty and unveil novel ways to improve the quality and extend the duration of life -these gains can be measured at both individual and population levels. For example, heart disease and cancer combined make up approximately half of all deaths in the United States per year, and already, advances in nanomedicine demonstrate great potential to reduce rates of morbidity and mortality due to these diseases. Meanwhile, public health applications of nanomedicine such as rapid and portable diagnostics and more effective vaccinations have the potential to revolutionize global health. Research driven by innovators across disciplines such as engineering, biology, medicine, and public health should collaborate in order to achieve maximal potential impact in health for individuals and populations. In turn, knowledge gaps regarding the potential health and safety implications of exposure to engineered nanomaterials must be continuously addressed and actively researched. Dynamic, proactive, and socially responsible research will drive nanomedicine as it plays an increasingly integral and transformative role in medicine and public health in the 21st century.
The confluence of nanotechnology and medicine: Nanomedicine is poised to revolutionize the delivery of health care to individuals and populations in the 21st century. Every medical specialty stands to be impacted as emerging nanotechnologies propel modalities for prevention, screening, diagnosis, and treatment. Medical interventions targeting vascular disease are becoming increasingly important, given current epidemiologic trends in morbidity and mortality due to these diseases. Vascular disease is a term that encompasses a collection of pathologies that affect the vessels (arteries, veins, and lymphatics) or vasculature in the body. The purpose of this article is to highlight current and emerging nanotechnologies aimed at vascular disease. Select, clinically relevant examples are described in the categories of drugs and drug delivery, imaging, sensors, biomaterials, diagnostics, and novel therapeutics. Several promising nanomedicine applications that target vascular disease are currently under various stages of development from bench top research to clinical trials. Given the rate of investment, promising research results and progression of many products to market nanomedicine applications in the prevention, diagnosis, and treatment of vascular disease holds great promise for improving the stand of care.
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