Background Peer-based exercise interventions that cultivate new opportunities for support with a fellow cancer survivor may result in increased exercise volume. It is not clear whether adding qualified exercise professional (QEP) support to peer-based interventions improves health outcomes. Therefore, the purpose of this study is to determine whether breast cancer survivor (BCS) dyads who receive 10 weekly sessions of virtually delivered QEP support have improved outcomes compared to BCS dyads who do not receive QEP support. Methods Participants Adult BCS with medical clearance for exercise, who have an internet-connected device, and currently engage in < 150 min of moderate-intensity exercise per week. Intervention BCS will be matched using evidence-based criteria. The intervention group will receive dyadic exercise information sessions and a program tailored by a QEP for 10 weeks (intervention period) and have access to the QEP for an additional 4 weeks (tapering period). The control will not receive any QEP support. Outcomes The primary outcome is post-intervention self-reported exercise volume. Secondary outcomes include device-assessed exercise volume (i.e., Fitbit), social support, and health-related quality of life. Randomization 108 participants, matched in dyads, will be randomized 1:1 to the MatchQEP or Match groups using a web-based scheme. Statistical analysis Outcomes will be measured at baseline, post-intervention, post-tapering, and at 12 weeks post-intervention follow-up. Discussion The findings from this RCT will determine if matched BCS dyads who receive 10 weeks of virtually delivered QEP support have higher levels of self-report and device-measured exercise, social support, and health related quality of life compared to matched dyads without QEP-delivered exercise guidance. To our knowledge this will be the first study to assess the combined effect of peer- and QEP support on exercise volume. Project findings will inform and optimize intervention methods aimed to increase exercise among BCS through accessible exercise supports. Trial Registration: The study is registered on ClinicalTrials.gov (study identifier: NCT04771975, protocol Version Number: 2, date: July 22, 2021).

Background: Social support is known to facilitate exercise among individuals with cancer; however, this support usually comes from a known source. The use of peer support, from an unknown peer, may facilitate exercise in survivors; however, this has not been well explored in the literature. Purpose: To examine the literature regarding the use, parameters, matching characteristics, and effectiveness of peer support physical activity interventions partnering unknown peers for individuals living beyond a cancer diagnosis. Methods: Six databases were searched for relevant reports up to December 17, 2021. Title/abstract screening, full-text review, and data extraction were completed in duplicate. Data were extracted for information on population, intervention and partner matching characteristics, and study outcomes. A qualitative synthesis was used to summarize findings and descriptive statistics were used to summarize applicable results. Results: Twelve reports were included in this review, describing 6 unique partner-based peer support physical activity interventions. Most interventions (83%) incorporated peers using a mentor/mentee relationship, where one peer acted as a topic “expert,” assisting the other peer around physical activity. All peers were “unknown” prior to the intervention and all interventions described physical activity level as a primary outcome. All articles including results demonstrated that peer support interventions led to significantly higher levels of physical activity post-treatment. Discussion: Promoting social support via unknown peers has potential to improve physical activity behavior in individuals living beyond a cancer diagnosis. Further research should examine the most appropriate mode of partner communication and the overall effectiveness of these interventions using social support as a primary outcome.

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