This review summarizes the available evidence in the literature on the etiology, diagnosis, management, and prevention of vesicovaginal, urethrovaginal, ureterovaginal, vesicocervical, and vesicouterine fistulae. Urogenital fistula is divided by origin: obstetric fistula occurring predominantly in developing countries and iatrogenic fistula, the most common cause in developed countries.

IL-6 is upregulated after retinal I/R injury, and its expression by microglia/phagocytic cells may protect RGC layer neurons from I/R injury. Exogenously added IL-6 protects the inner retina after I/R injury.