Digoxin did not reduce overall mortality, but it reduced the rate of hospitalization both overall and for worsening heart failure. These findings define more precisely the role of digoxin in the management of chronic heart failure.
A severe, transient granulocytopenia occurs shortly after the beginning of hemodialysis in the dog, as has been previously shown in man. Simultaneous blood sampling across the pulmonary vascular bed indicates that the process of granulocyte removal begins almost instantaneously and that the pulmonary vascular bed is a major site of granulocyte sequestration.
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