We report a patient who presented with acute abdominal pain during the COVID-19 pandemic. His work-up revealed rupture of a 5.8 cm abdominal aortic aneurysm. He also had fever, cough, and shortness of breath and radiologic evidence of COVID-19 infection. After careful consideration, he underwent successful endovascular repair under local anesthesia with good short-term results.
Lemierre's syndrome is characterized by septic thrombophlebitis of the internal jugular vein. It typically presents in healthy adolescents or young adults, usually preceded by an oropharyngeal infection, with the most common offending pathogen being Fusobacterium necrophorum. We present a case of Lemierre's syndrome in an elderly woman without antecedent oropharyngeal infection, caused by Streptococcus pyogenes. She was successfully treated with combined surgical and medical management.
Coronavirus disease 2019 (COVID-19) is an infectious disease typically manifested as a respiratory infection with a range of symptoms from a mild viral illness to a severe acute respiratory syndrome with multiorgan failure and death. We report a case of a young man presenting with compartment syndrome secondary to COVID-19 viral myositis, with a protracted hospital course further complicated by extensive venous and arterial thrombosis. As the coronavirus pandemic evolves, our understanding of the virus continues to improve; however, a host of unanswered questions remain about atypical presentation and management and treatment options.
Incorporation of [1-14C]glucosamine by acid-precipitable protein was enhanced in intestinal slices by isoproterenol, epinephrine, theophylline, and dibutyryl cyclic AMP. Moreover, the effect of either isoproterenol or epinephrine on [1-14C]glucosamine incorporation was markedly potentiated by the addition of theophylline. Uptake of [1-14C]glucosamine into the acid-soluble compartment of intestinal slices was not significantly affected by isoproterenol, epinephrine, or theophylline.The stimulatory effect of isoproterenol and theophylline was completely inhibited by cycloheximide. Subfractionation of intestinal slice homogenates indicated that increased synthesis was not confined to one glycoprotein class but appeared to effect mucins and glycocalyx glycoproteins equally. These results indicate that β-adrenergic hormones and cyclic AMP stimulate intestinal glycoprotein synthesis and may control the production of glycoproteins located at the intestinal surface.
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