Expression of the lymphoendothelial marker membrane mucoprotein podoplanin (podo) distinguishes endothelial cells of both blood and lymphatic lineages. We have previously discovered two distinct subpopulations of lymphatic endothelial cells (LECs) in human skin that were defined by their cell surface densities of podoplanin and were designated LEC podo-low and LEC -containing precollector vessels constitute a specialized segment of the initial lymphatic microvasculature, and we hypothesize that these LEC podo-low -containing vessels are involved in the trafficking of CCR10 ؉ T cells during skin inflammation.

Component-based testing and the whole-allergen CAP are equally relevant in the diagnosis of grass-, birch- and cat-allergic patients. Although slightly less sensitive, the microarray is sufficient for the diagnosis of HDM-allergic patients, but needs alternative and/or additional components for detecting mugwort allergy.

The production of target consonant clusters at early stages of acquisition is analysed from a phonological representational perspective. The data stem from five normal monolingual German and four normal monolingual Spanish children at ages from 0;9 to 2;1, observed in naturalistic settings. At the beginning stages, target clusters are reduced to a single consonantal position, due to lack of branching of the syllabic constituents. This finding coincides with other results in the literature, which have in general been explained by means of universal principles. Nevertheless, there is an essential difference between the German and the Spanish data: German children tend to prefer the first consonant and Spanish children the second one. This difference can only be explained in terms of parameterization of syllabification, which in German takes place from left to right and in Spanish from right to left. At later stages, when clusters begin to be produced with two consonantal positions, they offer evidence for the beginning of branching of syllabic constituents, due to parameterization, and for the chronological order of the setting of the subsyllabic parameters. Our data offer evidence in favour of the following acquisitional hierarchy: CV > CVC > CVCC > CCVCC.

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We present an accurate tool for exactly calculating SPT wheal size in mm(2).