Predominantly undifferentiated tumors occurring in the cerebrum of young individuals are referred to as “primitive neuroectodermal tumors.” Twenty‐three of these cases were collected which had certain common features. Grossly they tended to be cystic and compressed adjacent brain. Microscopically they were malignant‐appearing and demonstrated a prominent mesenchymal component. Sixteen cases showed focal evidence of glial and/or neuronal‐appearing differentiation. It is suggested that the mesenchyme is also an aspect of tumor differentiation. The biologic behavior of these tumors was malignant, with an average duration of 18 months from onset of symptoms to death.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.