With the exception of intestinal lymphoma, surgery is the most commonly recommended treatment for solitary feline intestinal tumours. However, there is a lack of evidence to substantiate resection margin recommendations for these tumours. The aim of this study was to add knowledge concerning resection margins for discrete intestinal masses in cats. Thirty confirmed feline intestinal tumours removed at veterinary centres across the UK from March 2017 to March 2018 underwent histological assessment at the palpable edge of the intestinal tumour and then at every 1 cm increment to the surgeon‐cut tissue border in oral, aboral and mesenteric directions. Histological margin recommendations were developed for carcinoma and lymphoma tumour types and non‐lymphoma intestinal tumours collectively. Seventeen intestinal lymphomas, nine carcinomas, two sarcomas and two mast cell tumours were evaluated in this study. Seven of the nine intestinal carcinomas would have been completely removed with histological margins of 4 cm in oral and aboral directions. Both sarcomas and one mast cell tumour would have been removed in their entirety with 4 cm histological margins in oral and aboral directions. There was extensive and varied microscopic invasion of intestinal tissue away from discrete intestinal lymphomas in the majority of the cases in this study. There is increasing evidence in veterinary as well as human literature supporting the role of surgical resection in the treatment of discrete intestinal lymphoma. If surgery is to be considered this study supports the removal of the gross tumour only. A histological margin of 4 cm should be considered, where possible, for intestinal masses other than lymphomas.
There is currently a lack of evidence‐based guidance when determining surgical margins for small intestinal tumours in dogs. The purpose of this study is to help the surgeon make informed clinical decisions about margins when confronted with a small intestinal mass. Twenty‐seven canine small intestinal tumours were histologically diagnosed and then had further histological assessment at every centimeter from the edge of the palpable tumour to the surgical margin in oral, aboral and mesenteric directions. In all 10 carcinomas a 3 cm tissue margin in oral, aboral and mesenteric directions would have resulted in complete tumour resection. In all 11 sarcomas a 2 cm tissue margin in oral, aboral and mesenteric directions would have resulted in complete tumour resection. Five of the six intestinal lymphomas would have required tissue margins of 4 cm or more for complete resection. Of the 21 non‐lymphoma tumours assessed in this study, complete resection was achieved in all 21 (100%) with tissue margins at 3 cm from the palpable edge of the mass, 20 (95%) with tissue margins at 2 cm from the palpable edge of the mass, and 16 (76%) with tissue margins at 1 cm from the palpable edge of the mass in oral and aboral directions. All non‐lymphoma canine small intestinal masses will be completely resected when tissue margins are 3 cm from the palpable edge of the mass in oral and aboral directions after fixation in formalin.
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