Female to male transgender mastectomy can be performed with low complication rates and high satisfaction. Nipple-sparing mastectomy were more likely to have a hematoma than patients undergoing MFNG.

Background and objectives: Increasing demand for live-donor kidneys has encouraged the use of obese donors despite the absence of long-term outcome data and evidence that obesity can adversely affect renal function. We wished to determine whether obesity increased the risk for renal dysfunction and other medical comorbidities in donors several years after donation.Design, setting, participants, & measurements: Ninety-eight patients who donated a kidney 5 to 40 years previously were stratified according to body mass index (BMI) at donation and evaluated for renal dysfunction and risk factors for cardiovascular disease. Patients who were from the 2005 through 2006 National Health and Nutrition Examination Survey database; did not have renal disease; and were matched for age, gender, race, and BMI served as two-kidney control subjects.Results: Renal function in obese (BMI >30) and nonobese (BMI <30) donors was similar, and both donor groups had reduced renal function compared with BMI-matched two-kidney control subjects. Obesity was associated with more hypertension and dyslipidemias in both donors and two-kidney control subjects; however, there were no significant differences between the two groups within each BMI category.Conclusions: These results indicate that obese donors are not at higher risk for long-term reduced renal function compared with nonobese donors and that the increased incidence of hypertension and other cardiovascular disease risk factors in obese donors is due to their obesity and is not further exacerbated by nephrectomy. These findings support the current practice of using otherwise healthy overweight and obese donors but emphasize the need for more intensive preoperative education and postoperative health care maintenance in this donor group.

Therapeutic, III.

Research conducted by evolutionary psychologists and biologists shows that subtle individual differences in body morphology can be related to surprising and important differences in human behavior and reproductive success. The authors summarize recent work on these effects as they relate to fluctuating asymmetry, facial attractiveness, finger digit morphology, sexually dimorphic differences in body configuration, and head circumference. Examples include the discovery that women who have sex with bilaterally symmetrical men report more orgasms; men with attractive faces have higher quality sperm; the length of the index finger in relation to the ring finger is related to verbal fluency, spatial ability, and the risk of autism; women with an hourglass figure have more regular menstrual cycles and are more fertile; and the sound of a person's voice predicts his or her sexual behavior.

Early development can have long-term effects on physiology and behavior. While severe disturbances predictably lead to dysfunction, recent work in humans and animals has led to a growing appreciation for the more subtle ways in which early conditions can modulate behavioral tendencies later in life. Life history theory predicts that early cues signaling a stressful or suboptimal environment might lead an organism to adopt a strategy favoring short-term gains and early reproduction. Fifty college men reported their birth weight, completed the Attention-Deficit/Hyperactivity Disorder (ADHD) SelfReport Scale, and answered a series of questions about their sexual history and attitudes towards short-term sexual encounters. Lower birth weights were associated with higher scores on the ADHD scale (r = -.352; p ≤ .05) and more favorable attitudes towards casual sex (r = -.456; p ≤ 0.001). There was a significant interaction between birth weight and casual sex favorability in predicting number of sexual partners (F 1,46 = 4.994; p ≤ .05). This suggests that, although men who are smaller at birth may otherwise be at a disadvantage in reproductive terms, they may offset their reduced fitness by being more willing to engage in casual sex.

No abstract

Abstract. Disgust is a universal emotion that promotes protective behaviors in three distinct domains: sexual, moral, and pathogenic. There is considerable individual variation in sensitivity to disgust, and past research suggests individuals with slower life history strategies are more sensitive to stimuli that provoke pathogen and moral disgust. We hypothesized that such individuals would also be more sensitive to disgust in a sexual context. Two hundred seventyseven participants completed the Mini-K Life History Battery and the Three Domains of Disgust Scale. A slower life history strategy (as reflected by a higher Mini-K score) was associated with increased sensitivity to sexual, pathogen, and moral disgust. Removal of items with potential overlap did not affect the significance of the results. These findings suggest that the K-factor of life history is associated with increased disgust sensitivity across all three domains.

Contrafreeloading involves working unnecessarily to obtain a reward that is otherwise freely available. It has been observed in numerous species and can be adaptive when it provides an organism with updated information about available resources. Humans frequently update their knowledge of the environment through checking behaviors. Compulsive checking occurs when such actions are performed with excessive frequency. In a putative animal model of compulsive checking, rats treated chronically with the dopamine agonist quinpirole display exaggerated contrafreeloading for water. Although this effect has been attributed to behavioral rigidity, some evidence suggests the behavior remains somewhat flexible and may be adaptive under certain conditions. We assessed the ability of quinpirole-treated rats with contrafreeloading experience to adapt to changing contingencies by requiring them to alternate between response levers. Rats treated with quinpirole or saline were first trained to obtain water by pressing either of two levers. Next, free water was made available for 8 days, and contrafreeloading was measured. Rates of contrafreeloading were significantly higher in the drug-treated rats than in controls. On the following 5 days, each reward caused the associated lever to become inactive until a reward was earned from the alternate lever. Quinpirole-treated rats learned this new response requirement more quickly than controls. Thus, exaggerated checking behavior induced by chronic quinpirole treatment can be advantageous when environmental contingencies change. These results provide support for this animal model of compulsive checking and hint at the presence of a specialized neural checking module involving the dopamine system.