Background: Bacterial promoters, which increase the efficiency of gene expression, differ from other promoters by several characteristics. This difference, not yet widely exploited in bioinformatics, looks promising for the development of relevant computational tools to search for strong promoters in bacterial genomes.
Abstract. Two approaches to logic programming with probabilities emerged over time: bayesian reasoning and probabilistic satisfiability (PSAT). The attractiveness of the former is in tying the logic programming research to the body of work on Bayes networks. The second approach ties computationally reasoning about probabilities with linear programming, and allows for natural expression of imprecision in probabilities via the use of intervals. In this paper we construct precise semantics for one PSAT-based formalism for reasoning with inteval probabilities, probabilistic logic programs (p-programs), orignally considered by Ng and Subrahmanian. We show that the probability ranges of atoms and formulas in p-programs cannot be expressed as single intervals. We construct the prescise description of the set of models of p-programs and study the computational complexity if this problem, as well as the problem of consistency of a p-program. We also study the conditions under which our semantics coincides with the single-interval semantics originally proposed by Ng and Subrahmanian for p-programs. Our work sheds light on the complexity of construction of reasoning formalisms for imprecise probabilities and suggests that interval probabilities alone are inadequate to support such reasoning.
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