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The current paper reports long-term treatment impact estimates for a randomized evaluation of an early childhood intervention designed to promote children's developmental outcomes and improve the quality of Head Start centers serving high-violence and high-crime areas in inner-city Chicago. Initial evaluations of end-of-preschool data reported that the program led to reductions in child behavioral problems and gains in measures of executive function and academic achievement. For this report, we analyzed adolescent follow-up data taken 10 to 11 years after program completion. We found evidence that the program had positive long-term effects on students’ executive function and grades, though effects were somewhat imprecise and dependent on the inclusion of baseline covariates. Results also indicated that treated children had heightened sensitivity to emotional stimuli, and we found no evidence of long-run effects on measures of behavioral problems. These findings raise the possibility that developing programs that improve on the Head Start model could carry long-run benefits for affected children.

Background DSM-5 proposes an Attenuated Psychosis Syndrome (APS) for further investigation, based upon the Attenuated Positive Symptom Syndrome (APSS) in the Structured Interview for Psychosis-Risk Syndromes (SIPS). SIPS Unusual Thought Content, Disorganized Communication and Total Disorganization scores predicted progression to psychosis in a 2015 NAPLS-2 Consortium report. We sought to independently replicate this in a large single-site high-risk cohort, and identify baseline demographic and clinical predictors beyond current APS/APSS criteria. Method We prospectively studied 200 participants meeting criteria for both the SIPS APSS and DSM-5 APS. SIPS scores, demographics, family history of psychosis, DSM Axis-I diagnoses, schizotypy, and social and role functioning were assessed at baseline, with follow-up every 3 months for 2 years. Results The conversion rate was 30% (n = 60), or 37.7% excluding participants who were followed under 2 years. This rate was stable across time. Conversion time averaged 7.97 months for 60% who developed schizophrenia and 15.68 for other psychoses. Mean conversion age was 20.3 for males and 23.5 for females. Attenuated odd ideas and thought disorder appear to be the positive symptoms which best predict psychosis in a logistic regression. Total negative symptom score, Asian/Pacific Islander and Black/African-American race were also predictive. As no Axis-I diagnosis or schizotypy predicted conversion, the APS is supported as a distinct syndrome. In addition, cannabis use disorder did not increase risk of conversion to psychosis. Conclusions NAPLS SIPS findings were replicated while controlling for clinical and demographic factors, strongly supporting the validity of the SIPS APSS and DSM-5 APS diagnosis.

Critical consciousness (CC) has emerged as a framework for understanding how low-income and racial/ethnic minority youth recognize, interpret, and work to change the experiences and systems of oppression that they face in their daily lives. Despite this, relatively little is known about how youths' experiences with economic hardship and structural oppression shape how they "read their world" and motivate participation in critical action behaviors. We explore this issue using a mixed-methods design and present our findings in two studies. In Study 1 we examine the types of issues that a sample of low-income and predominantly racial/ethnic minority youth (ages 13-17) living in the Chicago area discuss when asked to reflect on issues that are important to them. The most commonly mentioned themes were community violence (59%), prejudice and intolerance (31%), world issues (25%), and economic disparities (18%). In Study 2 we examine youths' quantitative reports of engaging in critical action behavior; more than 65% had participated in at least one activity targeting social change in the previous 6 months. We then examined relationships between youths' experiences with poverty within their households and neighborhoods, neighborhood income inequality, and exposure to violence and youths' likelihood of participating in critical action behaviors. Greater exposure to violence and neighborhood income inequality were related to an increased likelihood of engaging in critical action behaviors. This work highlights the diverse ways that low-income and racial/ethnic minority youth reflect on societal inequality and their commitment to effecting change through sociopolitical participation.

The prediction model performed well in classifying converters and non-converters and revealed SIPS measures that are relatively strong predictors of conversion, comparable with the risk calculator published by NAPLS (c-index = 0.71), but requiring only a structured clinical interview. Future work will seek to externally validate the model and enhance its performance with the incorporation of relevant biomarkers.