Many states across the United States have significant rural populations, which typically face different sets of challenges than those closer to urban populations. This is particularly evident in the different types of opportunities that small businesses face in those rural areas. In recent years, various efforts - both at a national and local level - have been taken to increase those opportunities for rural small businesses. However, those efforts have not always produced the results that are envisioned. Utilizing information about Small Business Development Center (SBDC) strategies to serve small businesses in both rural and urban areas, we highlight the efforts that work to aid rural entrepreneurs as well as those that fall short.
We consider high-dimensional generalized linear models when the covariates are contaminated by measurement error. Estimates from errors-in-variables regression models are well-known to be biased in traditional low-dimensional settings if the error is unincorporated. Such models have recently become of interest when regularizing penalties are added to the estimation procedure.Unfortunately, correcting for the mismeasurements can add undue computational difficulties onto the optimization, which a new tool set for practitioners to successfully use the models. We investigate a general procedure that utilizes the recently proposed Imputation-Regularized Optimization algorithm for high-dimensional errors-in-variables models, which we implement for continuous, binary, and count response type. Crucially, our method allows for off-the-shelf linear regression methods to be employed in the presence of contaminated covariates. We apply our correction to gene microarray data, and
We consider a framework for determining and estimating the conditional pairwise relationships of variables when the observed samples are contaminated with measurement error in high dimensional settings. Assuming the true underlying variables follow a multivariate Gaussian distribution, if no measurement error is present, this problem is often solved by estimating the precision matrix under sparsity constraints. However, when measurement error is present, not correcting for it leads to inconsistent estimates of the precision matrix and poor identification of relationships. We propose a new Bayesian methodology to correct for the measurement error from the observed samples.This Bayesian procedure utilizes a recent variant of the spike-and-slab Lasso to obtain a point estimate of the precision matrix, and corrects for the contamination via the recently proposed Imputation-Regularization Optimization procedure designed for missing data. Our method is shown to perform better than the naive method that ignores measurement error in both identification and estimation accuracy. To show the utility of the method, we apply the new method to establish a conditional gene network from a microarray dataset.
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