Traumatic brain injury and other neurological disorders continue to affect many worldwide and demand further research. It has been shown that electrical signaling and ion channel flow and dynamics are disrupted over the course of a traumatic brain injury as well as over the course of other neurological disorders. However, typical devices used to measure ion flow and electrical signaling from the brain suffer from complexity, high expense, poor spacial and temporal resolution, and low signal to noise ratios. Graphene has emerged as an economical and simple alternative to sensing electrical and ionic signals in a variety of biological situations. This material has emerged as a power material due to its excellent strength, electrical conductivity, and biocompatibility. This review paper focuses on the advantages of the different graphene-based electronic devices and how these devices are being developed into biosensors capable of sensing neuronal ionic and electrical activity and activity from other electrically excitable cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.