Acute Respiratory Infection (ARI) is one of the leading common causes of death in young children in Bangladesh. Three hundred fifty one patients of ARI below five years of age are selected as per WHO guidelines. Out of 351 patients, one patient died due to very severe pneumonia with severe malnutrition. There was male preponderance in all the age groups and also 41% of male children had recurrent attacks of ARI. In this study, it was statistically proved that malnutrition (p=Q.00028) and smoking habits of parents (p=0.04054) had significant important risk factors on recurrent attacks of ARI.
Fifty children with Kala-azar {27 male (54%) and 23 female (46%)} aged between 2-12 yrs, were studied retrospectively in the pediatric unit of Rajshahi Medical College Hospital to find out the optimal treatment of Kala-azar in children. Sodium stibogluconate was given intravenously at a dose of 10 mg/kbw/day for 20 days in one group (Group-A), 15 mg/kbw/day for 20 days in another group (Group-B), 10 mg/kbw/day B.D. for 20 days in another group (Group-C), and 20 mg/kg of body wt/day for 40 days is last group (Group-D). The apparent cure rates of all regimens were 100%. Side effects of sodium stibogluconate were mild, however, myocarditis developed on 37th day of treatment in one patient which reversed to normal after discontinuation of the drug. 27 patients (54%) could be followed up to six months after discharge from hospital. Two patients in group-A relapsed and none relapsed from group B, C or D. Follow-up of patients in group B, C and D showed improvement in general condition, increase in body weight, Hb% and regression of the size of the liver and spleen and ultimate rate of cure in B, C, D regimens were 100%. But ultimate cure rate in-group A was 71.4% and the significance of difference between A and other regimens (P<0.10) were statistically significant. Sodium stibogluconate 15mg/kg body weight once daily for 20 days (Group-B) had the best of cure rate with low toxicity and may be recommended for routine treatment of childhood Kala-azar in this country. doi: 10.3329/taj.v17i2.3455 TAJ 2004; 17(2): 99-103
Niemann Pick disease is a metabolic disorder, a fatal disorder of infancy characterized by delayed developmental mile stone, failure to thrive, hepatosplenomegaly and rapidly progressive neurodegenerative changes. A 16 month female child was admitted in IBMCHR with the complaints of convulsion with ARI. She had recurrent history of ARI & convulsion. She had failure to thrive, hepatosplenomegaly delayed developmental mile stone. He was diagnosed as a case of NPD with Seizure disorder. He was treated with anticonvulsant drugs & some injectable medication as a conjurvative treatment. She was discharged with further advice & ultimately the child died. DOI: 10.3329/taj.v22i1.5038 TAJ 2009; 22(1): 139-141
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