The first pediatric coronavirus disease 2019 (COVID-19) case was confirmed in Shenzhen, China on January 20, 2020. At the beginning of the outbreak, COVID-19 pneumonia was more common in adults than in children and adolescents, and the rate of confirmed pediatric cases was relatively lower. However, as screening tests and pathogen detection campaigns were initiated in more regions as the outbreak spread, the number of pediatric infection cases increased significantly. Currently, studies on pediatric COVID-19 are limited in the literature to case reports and case series, and a few epidemiological studies. COVID-19 has distinct characteristics in the pediatric population compared to adults; therefore, we need to better understand the characteristics of this disease in children. Discovering the characteristics of the pediatric COVID-19 disease is important for contributing to the diagnosis and treatment of the disease in this population. In this review, clinical characteristics, epidemiology, diagnosis, and management of pediatric COVID-19 pneumonia based on the recent literature are discussed. [ Pediatr Ann . 2020;49(7):e319–e325.]
To evaluate the predictive roles of biochemical and complete blood count parameters in the diagnosis of febrile seizures by comparing these between patients with simple febrile seizures and febrile patients without seizures. Methods: One hundred fifty-two children (66 girls and 86 boys), aged 6-60 months presenting with fever symptoms presenting to our hospital's pediatric emergency department between January 2015 and January 2020 were included in the study. Demographic data, complete blood count parameters and biochemical parameter levels were compared between the two groups. These were divided into a patient group with simple febrile seizures (n = 74) and a febrile control group without seizures (n = 78). Results: Comparison of biochemical parameters revealed significantly higher glucose, CRP, and ALT levels in the febrile seizure group, while Ca and Na were significantly lower. Comparison of complete blood count parameters revealed significantly higher white blood cell (WBC), neutrophil, red cell distribution width, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) values in the febrile seizure group, while hemoglobin, hematocrit, mean corpuscular volume, lymphocytes, and mean platelet volume were significantly lower. Conclusions: We think that in addition to markers such as WBC, leukocytes, and CRP for evaluating inflammation in patients with febrile seizures, simple, easily available, and inexpensive tests such as NLR and PLR can also be useful for assessing inflammation.
AmAç: Astım; geri dönüşümlü diffüz alt havayolu obstrüksiyonu ve bunun sonucunda hipoksemi oluşumu ile karakterize kronik bir hastalıktır. Ataklar sırasında, merkezi sinir sisteminin hipoksiye maruz kalması ve hipotalamo-hipofizer-gonadal aksın nörohormonal düzeninde bozukluk olması sonucu, astımlı çocuklarda büyüme ve puberte süreci seyrinde seksüel maturasyonun etkilenebileceği ileri sürülmektedir. Ayrıca hastalığın klinik şiddeti, hastanın cinsiyeti, semptomların kontrol düzeyi ve atak sıklığı, astımda kullanılan tedaviler de büyüme parametrelerini ve puberte gelişimini etkileyebilir. Bu çalışmada; astımlı çocuklarda, pubertal gelişim evrelerinin, benzer yaştaki sağlıklı çocuklarla karşılaştırılması ve istatistiksel olarak değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Bu çalışma; Ocak 2007-Şubat 2010 tarihleri arasında, Çocuk Göğüs Hastalıkları Bilim Dalı polikliniğimizde, astım tanısı ile takip edilen 6-18 yaş arası hastaların, dosya kayıtları incelenerek retrospektif olarak yapılmıştır. Elde edilen verilerin istatistiksel analizi için SPSS 15.0 programı kullanılmış, istatistiksel analizlerde p<0.05 anlamlı olarak kabul edilmiştir.BulGulAr: Çalışmaya 31'i erkek (%47.7), 34'ü kız (%52.3) toplam 65 hasta ve 27'si erkek (%49.1), 28'i kız (%50.9) olmak üzere 55 sağlıklı çocuk dahil edildi. Puberte evreleri kızlarda (telarş, pubarş, aksillarş, menarş) ve erkeklerde (genital gelişim, pubarş, aksillarş) ayrı ayrı Tanner sınıflamasına göre değerlendirildi. Çalışma grubu ile kontrol grubu, kızlarda telarş başlama yaşı açısından karşılaştırıldığında, çalışma grubunda telarş başlama yaşı kontrol grubuna göre istatistiksel olarak anlamlı düşük bulundu (p=0.015). Çalışma ve kontrol grubunda erkekler, pubarş başlama yaşı açısından karşılaştırıldığında çalışma grubunda pubarş başlama yaşı kontrol grubuna göre istatistiksel olarak anlamlı düşük bulundu (p=0.023).Sonuç: Bu çalışmanın sonucunda; astımlı çocuklarda puberte bulgularından, kızlarda telarşın, erkeklerde pubarşın sağlıklı çocuklara göre erken başladığı kanaatına varılmıştır.
Aim: We aimed to reveal the similarities and differences between the rare and severe multisystem inflammatory syndrome (MIS-C) and active familial Mediterranean fever (FMF) disease in children. Our study may help in the early recognition of MIS-C syndrome in children and distinguish it from other diseases with similar symptoms.Methods: We evaluated the demographic and clinical characteristics, laboratory findings, treatments and outcomes of patients with MIS-C syndrome and active FMF.Results: The clinical and laboratory findings of a total of 66 patients hospitalized in our pediatric clinic with the diagnosis of active FMF (n: 42) and MIS-C syndrome (n: 24) were reviewed retrospectively. The reason for pediatric emergency admission was determined as resistant fever in all patients. When the clinical findings of the patients were compared, it was determined that joint and abdominal pain in the FMF group and vomiting, rash, cough, Lenfadenopati (LAP) and myalgia findings in the MIS-C group were statistically significantly higher (p
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