Schlüsselwörter: Geschichte, Fisteln, Darmkanal, Verdauungsphysiologie. Development of cannulation techniques in equinesA historical overview describes the development of fistulation in horses to investigate digestive physiology, pharmacology and gut microbiology. During the 19th century fistulation of saliva ducts became successfully, in the first half of the 20th century the cannulation of the gut, too. Especially since the 70ies of the last century permanent cannulation or fistulation of various parts of the alimentary tract became routine. Several valuable experiments were conducted, to clear the most important aspects of digestive physiology as enzyms, prae-and postileal digestibility, flow rates of water and electrolytes, gut microbiology and their metabolites etc. The results of experiments with fistulated horses were the basis to optimize practical feeding and to improve prevention and therapy of disturbances in the gut.
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