The increasing interest in developing efficient and effective optimization techniques has conducted researchers to turn their attention towards biology. It has been noticed that biology offers many clues for designing novel optimization techniques, these approaches exhibit self-organizing capabilities and permit the reachability of promising solutions without the existence of a central coordinator. In this paper we handle the problem of dynamic web service composition, by using the clonal selection algorithm. In order to assess the optimality rate of a given composition, we use the QOS attributes of the services involved in the workflow as well as, the semantic similarity between these components. The experimental evaluationshows that the proposed approach has a better performance in comparison with other approaches such as the genetic algorithm.
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