This clinical evaluation study suggested that ANX and ADHD seem to have significantly different neuro-cognitive features: Poorest outcomes were observed among children with ADHD; rather than problems of attention, inhibitory control deficits were the most prominent differences between ANX and ADHD; and the presence of ANX appears to have mitigating effect on ADHD-related impairments.

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ÖzetAmaç: Klasik antiepileptikler kadar etkili ancak daha az yan etkileri olan yeni kuşak antiepileptik ilaçlardan sıkça kullanılan lamotrijin (LTG) ve levetirasetamın (LEV) lipid profili üzerine etkisi araştırıldı. Gereç ve SummaryObjectives: We aimed to investigate the efficacy of two new generation antiepileptics, lamotrigine (LTG) and levetiracetam (LEV), on serum lipid levels, since they are reported to be as effective as classical antiepileptics but with fewer side effects. were measured. The patients' data were compared with a control group.Results: Twenty-one patients treated with LTG and 20 patients treated with LEV were included in this study. TC, triglycerides, LDL, VLDL, and HDL values were compared with 21 healthy control subjects. TC, triglycerides, LDL, VLDL, and HDL values showed no statistically significant differences between groups.Conclusion: Neither LEV nor LTG, which are new generation antiepileptics, affected blood lipid levels. We consider that they are safe to use in patients, especially those with atherosclerosis risk.

SummaryObjectives: Premenstrual dysphoric disorder (PMDD) is a condition characterized by psychiatric and somatic symptoms commonly seen in women of childbearing age. There are few studies investigating the prevalence of PMDD in patients with epilepsy. In this study we investigate the frequency of PMDD in epilepsy patients and evaluate the relationship between antiepileptic drugs and PMDD. Methods:The subjects were 93 women with epilepsy and 30 controls. Patients were divided into five subgroups according to their medications as carbamazepine, oxcarbazepine, valproic acide, lamotrigine, and levetiracetam. Each group were examined for the frequency of PMDD. In addition, the incidence of PMDD was compared according to antiepileptic drugs in subgroups.Results: The frequency of PMDD was similar in patients with and without epilepsy. Focal epilepsy group, especially temporal lobe epilepsy, has a higher incidence of PMDD, but similar results were also found in women without epilepsy. Looking at the relationship between antiepileptic treatments and PMDD, patients treated with lamotrigine had the lowest frequency. Conclusion:The frequency of PMDD was similar in patients with and without epilepsy. Focal epilepsy patients, especially temporal lobe epilepsy patients, had a higher incidence of PMDD. The LTG group had the lowest rate of PMDD. In terms of PMDD, LTG may be beneficial for young women with epilepsy.Key words: Epilepsy; Premenstrual dysphoric disorder; antiepileptic drugs. ÖzetAmaç: Premenstruel disforik bozukluk (PMDB) çocuk doğurma çağındaki kadınlarda sık görülen, psikiyatrik ve fiziksel semptomlarla seyreden bir durumdur. Epilepsi hastalarında PMDB sıklığını araştıran az sayıda çalışma vardır. Bu çalışmada kliniğimizde takipli epilepsi hastalarında PMDB sıklığı ve PMDB ile antiepileptik ilaçlar arasındaki ilişki araştırıldı. Gereç ve Yöntem:Epilepsi tanısı olan 93 hasta ve sağlıklı 30 kadın çalışmaya alındı. Hastalar, karbamazepin, okskarbazepin, valproik asit, lamotrijin ve levetirasetam kullanan hastalar olarak 5 alt gruba ayrıldı. PMDB sıklığı her bir grup için incelendi. Ayrıca PMDB görülme oranı gruplar arasında ve kontrol grubu ile karşılaştırıldı. Bulgular: PMDB sıklığı epilepsi hastalarında toplum verileri ve kontrol grubu ile benzer oranlarda bulundu. Jeneralize ve fokal epilepsi arasındaki farka bakıldığında fokal epilepsilerde, özellikle temporal lob epilepsilerinde PMDB oranı daha yüksek olmakla birlikte istatistiksel anlamlı farklılık bulunmadı. Antiepileptik ilaçlarla PMDB ilişkisine bakıldığında ise lamotrijin kullanan hastalarda PMDB sıklığının en düşük olduğu görüldü.Sonuç: Sonuç olarak; PMDB sıklığı epilepsi hastalarında toplum çalışmalarına benzer oranlarda bulundu. Jeneralize ve fokal epilepsi arasındaki farka bakıldığında fokal epilepsilerde ve özellikle temporal lob epilepsilerinde PMDB görülme oranı daha yüksek olmakla birlikte bu fark istatistiksel olarak anlamlı değildi. Lamotrijin kullanan hastalarda PMDB oranının en düşük olması, genç epilepsi hastası kadınlarda LTG kullanımının PMD...

IntroductionSexual dysfunction (SD) is defined as the deterioration of sexual response cycles caused by anatomic, physiologic or psychologic reasons.ObjectivesWe believe that SD is closely related to self-esteem and childhood trauma (CT).AimIn this study, the level of self-esteem and CT in patients diagnosed with SD vs. controls are aimed to be compared. In addition, relationship between complaints of SD self-esteem and CT variable subgroups are planned to be investigated.MethodTwenty-four patients visited Prof. Dr. Mazhar Osman Psychiatric Hospital with matching defined criteria and 24 control counterparts statistically matching were taken sociodemographic data form, Rosenberg Self-esteem Scale (RSS) and Childhood Trauma Questionnaire (CTQ-28) was applied.ResultsCTQ-28 averages and RSS variables which are sensitivity to criticism, depressive mood, psychosomatic symptoms, feeling threatened in interpersonal relationships, degree to participate in discussions, relationship with father were higher in patients with SD (P < 0.05). Considering the relationship between complaints of SD and CTQ-28 subscales, physical abuse, emotional abuse, physical neglect, emotional neglect averages of patients were observed significantly different rooted by genitopelvic pain/penetration disorder and premature ejaculation and in emotional neglect by premature ejaculation and low libido combination (P < 0.05).ConclusionsIn literature, there are many studies that show CT leads to SD and several studies state that self-esteem is affected in patients with SD [1]. CT must be considered and determined in the goal of treatment of SD.Disclosure of interestThe authors have not supplied their declaration of competing interest.