The objective of this study was to investigate the prevalence and to track associated risk facters of antibiotic resistant Salmonella, Entamoeba histolytica and Giardia lamblia in Harar, Easthen Ethiopia. A total of 384 stool samples were collected from Harar Hiwot-Fana Hospital and analyzed in Harari Regional Laboratory. The results of the study show that 96 (25%), 80 (20.6%) and 56 (14.6%) of the samples were positive for Salmonella, E. histolytica and G. lamblia, respectively. The antimicrobial sensitivity test showed that all (100%) of the Salmonella isolates were sensitive to ciprofloxacin while 85% were sensitive to nalidixic acid. Of the 56 (14.6%) Salmonella isolates, 100, 100, 85 and 71.2% were resistant to ampicillin, tetracycline, trimethoprim-sulfamethoxazole and chloramphenicol, respectively. This study indicates that Salmonella, E. histolytica and G. lamblia were prevalent in Harar and this enterophathogens should be considered routinely in the diagnosis of patients with diarrhoea. Moreover, physicians should also prescribe appropriate drugs either after sensitivity testing or in areas where there are no facilities for culturing; they have to refer updated information on local sensitivity patterns.
Foods of animal origin have been consistently implicated in sporadic cases and outbreaks of salmonellosis, and are widely acknowledged to be a significant reservoir for Salmonella. The usage of growth promoting agents (GPAs) in food animal production is a major public health threat that can contribute to the emergence of antimicrobial resistance bacteria. Extensive and improper use of antimicrobial drugs in food animal agriculture can also establish reservoirs of antimicrobial resistant bacteria, significantly impacting public health. There are an increased number of reports on antibiotic resistance and multiple drug resistant salmonellosis in developing countries caused by both Salmonella typhi and non-typhoidal Salmonella species. In Ethiopoia, there have been studies conducted on salmonellosis which suggest an increase in the antimicrobial resistance of Salmonella to commonly used antimicrobials in both public health and veterinary sectors. For example, 31.8% of Salmonella isolates from sheep and goat, 44.4% of isolates from camels, 52% isolates from cattle and 87.2% isolates from minced beef and chicken were resistant to one or more antimicrobials commonly used to treat both human and animal infections. High proportion of Salmonella isolates developed resistance to the commonly prescribed antimicrobials and this may be a considerable risk in the treatment of clinical case. Therefore, isolation of drug resistant Salmonella strains from a wide range of sources, from humans, food animals and animal food products underlines the need for judicious use of antimicrobial agents in both clinical practice and animal husbandry, as well as the need for cooperative and coordinated surveillance and monitoring programs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.