Adult acute lymphoblastic leukaemia (ALL) is one of the most prevalent haematological malignancies in adults, accounting for about 20-30% of cases. The complete remission (CR) rate can reach 70-90% but more than 60% of patients still relapse when treated with intensive consolidation chemotherapies. Consequently, allogeneic haematopoietic stem cell transplantation (allo-HSCT) is considered the standard care for postremission treatment to reduce the risk of recurrence, albeit accompanied by high therapy-related mortality (TRM). 1,2 In recent years, superior results have been achieved in B cell-ALL (B-ALL) therapy and the role of allo-HSCT in first CR (CR1) patients is an area of active investigation. Recently, the emergence and rapid development of novel targeted therapies in B-ALL, including monoclonal antibodies against specific tumour antigens (inotuzumab, blinatumomab, etc.) and chimeric antigen receptor T cells characterized by a high response rate and acceptable tolerance, have been witnessed. [3][4][5] For adolescents and young adults, paediatric-inspired protocols may achieve comparable or even potentially better results without upfront allo-HSCT. 6 In Philadelphia chromosome-positive
In order to decrease and control electromagnetic pollution, absorbing materials with better electromagnetic wave absorption properties should be developed. In this paper, a nanocrystalline alloy ribbon with the composition of Fe73.2Si16.2B6.6Nb3Cu1 was designed and prepared. Nanocrystalline alloy powder was obtained by high-energy ball milling treatment. The effects of ball milling time on the soft magnetic properties, microstructure, morphology, and electromagnetic wave absorption properties of alloy powder were investigated. The results showed that, as time increased, α-(Fe, Si) gradually transformed into the amorphous phase, and the maximum saturation magnetization (Ms) reached 135.25 emu/g. The nanocrystalline alloy powder was flakelike, and the minimum average particle size of the powder reached 6.87 μm. The alloy powder obtained by ball milling for 12 h had the best electromagnetic absorption performance, and the minimum reflection loss RLmin at the frequency of 6.52 GHz reached −46.15 dB (matched thickness was 3.5 mm). As time increased, the best matched frequency moved to the high-frequency direction, and the best matched thickness decreased, while the maximum effective absorption bandwidth ΔfRL<−10 dB was 7.22 GHz (10.78–18 GHz).
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