Keeping the pressure of the automobile tire in the normal working range is an important guarantee for the safety of the automobile. When the tire leaks, the driver should be reminded to check or replace the tire before the potential danger of blowing out. Aiming at the safety problem of commercial vehicle driving, a set of tire pressure monitoring alarm systems is designed by combining the radius method and frequency method. The magneto-electric wheel speed sensor is used to collect and process the tire speed, and then through the data processing, the full range of monitoring each tire’s possible air leakage hazards, such as emergency can be quickly warned, thus providing a reference for the driver’s driving. The experimental results show that the system can effectively improve the accuracy and stability of tire pressure monitoring.

SummaryObjective To compare the efficacy and safety-related outcomes after radical prostatectomy (RP) and permanent seed implantation (PI) using iodine-125 seeds in patients with prostate cancer. Method A retrospective analysis of 196 patients with biopsy-confirmed prostate cancer (T2-T3) was performed in this study. Forty-five patients who underwent PI using iodine-125 seeds combined with endocrine therapy or androgen deprivation therapy (ADT) were compared with 151 patients who underwent RP combined with endocrine therapy or adjuvant ADT. The efficacy and safety outcomes were compared using Kaplan–Meier curves and t-tests. Results Between the RP and PI treatment modalities, no significant difference (P > 0.05) in biochemical recurrence-free survival (BRFS) was observed using Kaplan–Meier curves, regardless of the combination of adjuvant treatment modalities. Furthermore, no significant differences were observed (P > 0.05) with respect to PSA fluctuations, albumin, leukocyte count, urinary and rectal symptoms, erectile function or quality of life (QoL) between the two therapy methods. However, significant differences in the maximum flow rate, average length of hospital stay and indwelling catheter time were observed between the two groups (P < 0.001). Conclusion Iodine-125 seed implantation significantly shortened the average length of hospital stay and indwelling catheter time compared with RP, and the haemoglobin level was significantly higher in the PI group than in the RP group; however, the maximum urine flow rate was lower after of PI than after RP. These two methods showed similar BRFS rates among prostate cancer patients.

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Quantifying the number of progenitor cells that founder an organ, tissue or cell population is of fundamental value for understanding the development and homeostasis of a multicellular organism. Previous efforts rely on marker genes that are specifically expressed in progenitors. The strategy is, however, often hindered by the lack of ideal markers. By exploring the cell phylogenetic tree that records the cell division history during development, we here describe a general statistical method able to quantify the progenitors of any tissues or cell populations defined in an organism without progenitor-specific markers. The method, termed targeting coalescent analysis (TCA), computes for all cells of tissue the average coalescent rate at the monophyletic clades of the target tissue, the inverse of which then measures the progenitor number of the tissue. Both theoretical deduction and computer simulations supported the underlying logics of TCA, which was then validated by empirical data of nematode, fruit fly and mouse, all with required cell phylogenetic trees. We further showed that TCA can be used to identify lineage-specific gene expression upregulations during embryogenesis, revealing incipient cell fate commitments in mouse embryos.