Background
Endometrial and cervical polyps are masses of endometrium or cervical epithelium that bulge into the uterine or cervical lumen. The physiopathology and contributing factors of endometrial polyps development are still unknown.
Methods
Clinical and pathology records of 28 nonhuman primates with histologically confirmed endometrial and cervical polyps were reviewed. Twenty-one baboons with endometrial polyps were evaluated for age at diagnosis; body weight; menstrual cycle length, presence of endometriosis and adenomyosis; and number of offspring, cesarean sections, and stillbirths.
Results
Endometrial polyps in baboons were associated with increased age, decreased menstrual cycle lengths, endometriosis, and decreased parity. No differences were found for weight, adenomyosis, or number of cesarean sections or stillbirths.
Conclusions
Baboons are a promising model for the study of endometrial polyps because of their similarity to humans in both the development of endometrial polyps and association of many of the same risk factors.
SummaryWe have studied the hematology and hemoglobin patterns of normal and heterozygous j3 thalassemia infants in serial samples obtained during the first year of life. The hemoglobin level, mean cell volume and mean cell hemoglobin were significantly lower in the j3 thalassemia traits by the age of 3 months and this difference was maintained throughout the first year. Hb A2 levels were significantly higher in the j3 thalassemia group but increased in both groups throughout the first year. Hb F levels were also higher in heterozygotes for j3 thalassemia at all ages, showing a delay in the postnatal decline. Speculation pregnant women who were heterozygotes for P thalassemia. Those women whose husbands were shown not to carry the j 3 thalassemia gene were approached at delivery for permission to carry out blood sampling of their offspring at 3 monthly intervals after birth. In this way data on heterozygous P thalassemia children and an equal number of normal children could be obtained in an unbiased manner.The majority of these women were of Cypriot origin. In addition one patient each of Italian, Indian, Chinese and West Indian origin were included in the study.
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